Announcements Trials
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Phase

Phase 2 2Phase 3 1Phase 1 1

Status

Completed 4Terminated 1

Sponsor Class

INDUSTRY 3OTHER 1

Study Type

Interventional 4

Sponsor

Cancer Type

Other hematologic neoplasm 4Myeloid 2Breast 1

Conditions

Leukemia, Myelogenous, Chronic, BCR-ABL Positive 18Leukemia 4Breast Neoplasms 4Philadelphia Chromosome 3Neoplasms 3Neoplasm Metastasis 2Leukemia, Myeloid 2Bronchiolitis Obliterans Syndrome 2Uterine Cervical Neoplasms 1Urinary Bladder Neoplasms 1Translocation, Genetic 1Thymus Neoplasms 1Thymoma 1Pathologic Processes 1Ovarian Neoplasms 1Neoplasms by Histologic Type 1Mesothelioma 1Leukemia, Myeloid, Chronic-Phase 1Hematologic Diseases 1Glioblastoma 1Carcinoma, Non-Small-Cell Lung 1Bone Marrow Diseases 1Blast Crisis 1

Interventions

Cyclophosphamide 227Cytarabine 194fludarabine phosphate 138Methotrexate 132Filgrastim 127Busulfan 103Etoposide 99Peripheral Blood Stem Cell Transplantation 91Rituximab 81fludarabine 77Radiotherapy 77Vincristine 74Daunorubicin 68Antilymphocyte Serum 65Cyclosporine 63Dexamethasone 61Tacrolimus 56Mycophenolic Acid 53Melphalan 52Imatinib Mesylate 50Granulocyte Colony-Stimulating Factor 50Mercaptopurine 46Whole-Body Irradiation 45Idarubicin 43sargramostim 42Methylprednisolone 42Doxorubicin 41Flow Cytometry 40Prednisone 39Clofarabine 39

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Completed × Leukemia × bosutinib × Clear all
NCT02130557 2021-05-18

A Multicenter Phase 3, Open-Label Study of Bosutinib Versus Imatinib in Adult Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia

Pfizer

Phase 3 Completed
536 enrolled 24 charts 1 FDA
MyeloidOther hematologic neoplasm

Bronchiolitis Obliterans Syndrome, Bone Marrow Diseases, Hematologic Diseases, Leukemia, Leukemia, Myeloid, Neoplasms by Histologic Type, Pathologic Processes, Philadelphia Chromosome, Translocation, Genetic, Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT02638467 2020-11-05

Allogeneic Stem Cell Transplantation in Chronic Myeloid Leukemia Failing TKIs Therapy

University of Milano Bicocca

Phase 2 Completed
2 enrolled
Other hematologic neoplasm

Bronchiolitis Obliterans Syndrome, Leukemia

NCT00261846 2017-07-27

Study Evaluating SKI-606 (Bosutinib) In Philadelphia Chromosome Positive Leukemias

Pfizer

Phase 2 Completed
571 enrolled 48 charts
MyeloidOther hematologic neoplasm

Leukemia, Philadelphia Chromosome, Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT00777530 2008-10-23

Study Evaluating Ascending Single-Dose Of Bosutinib Administered With Multiple Doses Of Ketoconazole To Healthy Subjects

Wyeth is now a wholly owned subsidiary of Pfizer

Phase 1 Completed
48 enrolled
BreastOther hematologic neoplasm

Breast Neoplasms, Leukemia, Neoplasms

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