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1 trials

Recent Start date Enrollment

Phase 1 × Leukemia × pevonedistat × Clear all

Phase

Phase 3 1 Phase 1 1

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1

Conditions

Leukemia, Myeloid, Acute 9 Myelodysplastic Syndromes 5 Precursor Cell Lymphoblastic Leukemia-Lymphoma 2 Neoplasms 2 Multiple Myeloma 2 Lymphoma 2 Advanced Solid Neoplasm 2 Solid Tumors 1 Renal Insufficiency 1 Melanoma 1 Lymphoma, Non-Hodgkin 1 Lymphoma, Mantle-Cell 1 Lymphoma, Large B-Cell, Diffuse 1 Lymphoma, Follicular 1 Lymphoma, B-Cell, Marginal Zone 1 Liver Diseases 1 Leukemia, Prolymphocytic, B-Cell 1 Leukemia, Myelomonocytic, Chronic 1 Leukemia, Lymphocytic, Chronic, B-Cell 1 Leukemia 1 Hodgkin Disease 1 Hematologic Neoplasms 1 Central Nervous System Neoplasms 1 Advanced Solid Tumors 1 Advanced Nonhematologic Malignancies 1

Interventions

Cyclophosphamide 52 Cytarabine 49 fludarabine phosphate 38 fludarabine 32 Filgrastim 30 Etoposide 23 Rituximab 19 Azacitidine 17 Whole-Body Irradiation 16 Tacrolimus 14 Peripheral Blood Stem Cell Transplantation 13 Granulocyte Colony-Stimulating Factor 13 Decitabine 13 Clofarabine 13 venetoclax 12 Melphalan 12 Antilymphocyte Serum 12 Mycophenolic Acid 11 Methotrexate 11 Radiotherapy 10 Mitoxantrone 10 Daunorubicin 10 Busulfan 10 sargramostim 9 aldesleukin 9 Vincristine 9 Sirolimus 9 Topotecan 8 Idarubicin 8 Dexamethasone 8

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT04172844 2024-06-04

PAVE

Medical College of Wisconsin

Phase 1 Terminated

Other hematologic neoplasm

Leukemia, Leukemia, Myeloid, Acute

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