Clinical Trials
13 trialsNCT05237960 2026-04-20
Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia
University of Arizona
Phase 2 Active not recruiting
NCT02581137 2026-04-13
Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion
National Cancer Institute (NCI)
Phase 2 Active not recruiting
NCT06876038 2026-03-19
Low-cost Screening and Image-guided Photodynamic Therapy (PDT) of Premalignant and Malignant Oral Lesions
University of Massachusetts, Boston
Phase 2 Not yet recruiting
NCT07387900 2026-02-06
Evaluation of the Chemo-preventive Effect of Combined Topical and Systemic Metformin on Oral Leukoplakia
Cairo University
Phase 2 Recruiting
NCT05727761 2025-12-24
Pioglitazone-Metformin Combination Treatment for High Risk Oral Preneoplasia
University of Minnesota
Phase 2 Recruiting
NCT03692325 2024-10-01
Safety and Efficacy of Nivolumab in Treating Oral Proliferative Verrucous Leukoplakia
Dana-Farber Cancer Institute
Phase 2 Completed
NCT00099021 2022-02-11
Pioglitazone Hydrochloride in Preventing Head and Neck Cancer in Patients With Oral Leukoplakia
National Cancer Institute (NCI)
Phase 2 Completed
NCT00453336 2017-02-08
Photodynamic Therapy With Porfimer Sodium in Treating Patients With Precancerous Lesions, Cancer, or Other Disease of the Aerodigestive Tract
University of Miami
Phase 2 Completed
NCT00951379 2016-04-06
Pioglitazone for Oral Premalignant Lesions
National Cancer Institute (NCI)
Phase 2 Terminated
NCT00330382 2014-12-19
Bowman-Birk Inhibitor Concentrate in Preventing Cancer in Patients With Oral Leukoplakia
National Cancer Institute (NCI)
Phase 2 Completed
NCT00101335 2013-07-11
Celecoxib in Preventing Head and Neck Cancer in Patients With Oral Leukoplakia
Fox Chase Cancer Center
Phase 2 Completed
NCT00369174 2013-02-13
Rosiglitazone Maleate in Treating Patients With Oral Leukoplakia
National Cancer Institute (NCI)
Phase 2 Completed
NCT00176566 2009-12-11
A Phase II Trial to Assess the Effects of Green Tea in Oral Leukoplakia
Rutgers, The State University of New Jersey
Phase 2 Terminated