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Phase

Phase 3 9Phase 2 6Phase 1 4Phase 2/3 2Phase 1/2 2Phase NA 1Phase EARLY_PHASE1 1

Status

Completed 1Active not recruiting 1

Sponsor Class

NIH 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Sarcoma 2Plasma cell 1

Conditions

Lymphoma 6Breast Neoplasms 6Leukemia 5Precursor Cell Lymphoblastic Leukemia-Lymphoma 4Lymphoma, Large B-Cell, Diffuse 4Sarcoma 3Osteosarcoma 3Sarcoma, Synovial 2Sarcoma, Alveolar Soft Part 2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Ovarian Neoplasms 2Neurofibrosarcoma 2Liposarcoma 2Leukemia, T-Cell 2Leiomyosarcoma 2Histiocytoma, Malignant Fibrous 2Fibrosarcoma 2Fallopian Tube Neoplasms 2Chondrosarcoma, Extraskeletal Myxoid 2Triple Negative Breast Neoplasms 1Thymoma 1Thymic epithelial tumor 1The Neoadjuvant Therapy 1Sezary Syndrome 1Sarcoma, Ewing 1Sarcoma, Clear Cell 1Renal Pelvis and Ureter Urothelial Carcinoma 1Perivascular Epithelioid Cell Neoplasms 1Nerve Sheath Neoplasms 1Neoplasms, Connective and Soft Tissue 1

Interventions

Doxorubicin 2selinexor 1pazopanib 1brigimadlin 1Sugars 1Radiotherapy 1Radiation 1Ifosfamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 2/3 × Liposarcoma × Doxorubicin × Clear all
NCT02180867 2026-05-04

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

National Cancer Institute (NCI)

Phase 2/3 Active not recruiting
140 enrolled 22 charts
Plasma cellSarcoma

Histiocytoma, Angiomatoid Fibrous, Chondrosarcoma, Extraskeletal Myxoid, Fibrosarcoma, Granuloma, Plasma Cell, Leiomyosarcoma, Liposarcoma, Sarcoma, Sarcoma, Synovial, Chondrosarcoma, Mesenchymal, Dermatofibrosarcoma, Sarcoma, Clear Cell, Sarcoma, Alveolar Soft Part, Nerve Sheath Neoplasms, Neurofibrosarcoma, Histiocytoma, Malignant Fibrous, Perivascular Epithelioid Cell Neoplasms

NCT05218499 2026-03-02

Brightline-1: A Study to Compare Brigimadlin (BI 907828) With Doxorubicin in People With a Type of Cancer Called Dedifferentiated Liposarcoma

Boehringer Ingelheim

Phase 2/3 Completed
400 enrolled 15 charts
Sarcoma

Liposarcoma

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