Clinical Trials

240 enrolled

DermatologicGastrointestinalGenitourinaryOther solid neoplasmThoracic

Liver Cirrhosis, Liver Neoplasms

NCT06362369 2026-04-13

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

Phase 1/2 Recruiting

126 enrolled

Turcot syndrome, Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Kidney Neoplasms, Liver Neoplasms, Melanoma, Neoplasm Metastasis, Skin Neoplasms, Colorectal Neoplasms

NCT06753136 2026-04-13

Electrochemotherapy (ECT) in Patients With Primary Visceral Tumors and/or Secondary Visceral Localizations, of Any Histotype

DermatologicGastrointestinal

24 enrolled

Carcinoma, Squamous Cell, Liver Neoplasms, Melanoma, Carcinoma, Merkel Cell

NCT07227012 2026-04-08

Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

Phase 1/2 Recruiting

138 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT07517198 2026-04-08

Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

40 enrolled

Margins of Excision, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Liver Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT00451022 2026-04-07

Follow-Up Study of Subjects Previously Enrolled in Poxviral Vector Gene Transfer Studies

BreastGastrointestinalGenitourinaryThoracic

750 enrolled

Breast Neoplasms, Colonic Neoplasms, Liver Neoplasms, Lung Neoplasms, Prostatic Neoplasms

NCT05003895 2026-04-07

GPC3 Targeted CAR-T Cell Therapy in Advanced GPC3 Expressing Solid Tumor Malignancies

38 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT04715191 2026-04-06

Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

GastrointestinalGenitourinarySarcoma

24 enrolled

Liposarcoma, Liver Neoplasms, Wilms Tumor, Rhabdomyosarcoma, Endodermal Sinus Tumor, Rhabdoid Tumor

NCT06096779 2026-04-03

Kirros

Phase 2 Recruiting

30 enrolled

Digestive System Neoplasms, Fatty Liver, Fibrosis, Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms

NCT06342414 2026-04-03

ELUCIDATE

400 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms, Cholangiocarcinoma

NCT06486454 2026-03-31

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

5,000 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT06600321 2026-03-31

A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma

158 enrolled

Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms

NCT07124000 2026-03-31

DP-04

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

100 enrolled

Adenocarcinoma, Anus Neoplasms, Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Melanoma, Mouth Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Sarcoma, Testicular Neoplasms, Thyroid Neoplasms, Urethral Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Endometrial Neoplasms, Gastrointestinal Stromal Tumors, Small Cell Lung Carcinoma

NCT07504367 2026-03-31

Large Language Models Assist in Tumor MDT

BreastGastrointestinalThoracic

60 enrolled

Breast Neoplasms, Liver Neoplasms, Lung Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT07312292 2026-03-30

RADIANT

Phase 2 Recruiting

15 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms, Neoplasm Metastasis

NCT07377487 2026-03-30

INDIGO

EndocrineGastrointestinalNET

51 enrolled

Carcinoma, Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Colorectal Neoplasms, Carcinoma, Neuroendocrine, Neuroendocrine Tumors

NCT07500220 2026-03-30

DUET-HCC

Phase 1/2 Recruiting

30 enrolled

Simpson-Golabi-Behmel syndrome, Liver Neoplasms

NCT04390724 2026-03-27

Optimizing Y90 Therapy for Radiation Lobectomy

104 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms, Neoplasm Metastasis

NCT06687941 2026-03-27

A Study to Evaluate the Tolerability, Safety, and PK of AST-201 in Patients With GPC3-positive Advanced Solid Tumors

70 enrolled

GastrointestinalThoracic

Simpson-Golabi-Behmel syndrome, Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Liver Neoplasms, Neoplasm Metastasis, Neoplasms

NCT06447064 2026-03-25

(CLOCS-2)

GastrointestinalGenitourinaryGynecologic

2,900 enrolled

Urinary Bladder Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Liver Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Uterine Neoplasms, Vulvar Neoplasms, Endometrial Neoplasms

NCT06858813 2026-03-25

A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

232 enrolled

Liver Neoplasms

NCT06345508 2026-03-20

QUS in HCC

328 enrolled

Disease, Carcinoma, Hepatocellular, Liver Neoplasms

NCT07044362 2026-03-19

Histotripsy Plus Chemotherapy vs Chemotherapy Alone for Advanced Colorectal Liver Metastasis

100 enrolled