Clinical Trials

14 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms, Vaccinia

NCT06673329 2026-05-13

Brodalumab in the Treatment of Immune-Related Adverse Events

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckThoracic

11 enrolled

Brain Neoplasms, Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Mouth Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Thyroid Neoplasms

NCT03552718 2026-05-07

QUILT-2.025 NANT Neoepitope Yeast Vaccine (YE-NEO-001): Adjuvant Immunotherapy Using a Personalized Neoepitope Yeast-Based Vaccine To Induce T-Cell Responses In Subjects W/ Previously Treated Cancers.

BreastDermatologicGastrointestinalHead & NeckThoracic

5 enrolled

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Liver Neoplasms, Melanoma, Pancreatic Neoplasms, Colorectal Neoplasms

NCT06091930 2026-05-07

A Study to Test Different Doses of BI 765049 Alone and in Combination With Ezabenlimab in Asian People With Advanced Cancer (Solid Tumours) Positive for B7-H6

GastrointestinalHead & NeckThoracic

21 enrolled

Gastrointestinal Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT07430202 2026-05-06

A DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Glutamine Antagonist DRP-104, Nivolumab, and Ipilimumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)

Phase 1 Not yet recruiting

27 enrolled

Fibrolamellar hepatocellular carcinoma, Carcinoma, Liver Neoplasms

NCT06600321 2026-05-01

A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma

158 enrolled

Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms

NCT07053072 2026-04-23

PD-1 mRNA LNP Vaccine for Advanced Primary Hepatocellular Carcinoma.

9 enrolled

Liver Neoplasms

NCT02381561 2026-04-13

Ropidoxuridine in Treating Patients With Advanced Gastrointestinal Cancer Undergoing Radiation Therapy

19 enrolled

Colonic Neoplasms, Esophageal Neoplasms, Liver Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT07517198 2026-04-08

Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

40 enrolled

Margins of Excision, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Liver Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT05003895 2026-04-07

GPC3 Targeted CAR-T Cell Therapy in Advanced GPC3 Expressing Solid Tumor Malignancies

38 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT04715191 2026-04-06

Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

24 enrolled

Liposarcoma, Liver Neoplasms, Wilms Tumor, Rhabdomyosarcoma, Endodermal Sinus Tumor, Rhabdoid Tumor

NCT06687941 2026-03-27

A Study to Evaluate the Tolerability, Safety, and PK of AST-201 in Patients With GPC3-positive Advanced Solid Tumors

70 enrolled

GastrointestinalThoracic

Simpson-Golabi-Behmel syndrome, Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Liver Neoplasms, Neoplasm Metastasis, Neoplasms

NCT06858813 2026-03-25

A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

232 enrolled

Liver Neoplasms

NCT05411133 2026-03-19

Treatment of Cabotamig (ARB202) in Advanced Gastrointestinal Cancer Patients

33 enrolled

Phase 1 Not yet recruiting

Adenocarcinoma Of Esophagus, Gastrointestinal Neoplasms, Liver Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Cholangiocarcinoma

NCT07436988 2026-03-12

ReLIVE

18 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT03028311 2026-03-10

Yttrium Y-90 Radioembolization in Treating Patients With Metastatic Liver Cancer

12 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT05103631 2026-03-06

Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in Autologous T Cells for Solid Tumors

12 enrolled

Carcinoma, Hepatocellular, Liposarcoma, Liver Neoplasms, Wilms Tumor, Rhabdomyosarcoma, Endodermal Sinus Tumor, Rhabdoid Tumor

NCT07337525 2026-02-18

A First in Human Study of PLT012 in Participants With Solid Tumor Cancers

GastrointestinalGenitourinary

36 enrolled

Urinary Bladder Neoplasms, Gastrointestinal Neoplasms, Liver Neoplasms

NCT07148050 2026-02-17

IMPACT

21 enrolled

Carcinoma, Hepatocellular, Liposarcoma, Liver Neoplasms, Wilms Tumor, Rhabdomyosarcoma, Hepatoblastoma, Endodermal Sinus Tumor, Rhabdoid Tumor

NCT06440005 2026-02-11

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

BreastGastrointestinalGenitourinarySarcoma

80 enrolled

Breast Neoplasms, Hemangiosarcoma, Liver Neoplasms, Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT07390838 2026-02-05

A Study of SH009 Injection in Patients With Advanced Solid Tumors.

BreastGastrointestinalThoracic

150 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Stomach Neoplasms

NCT07362264 2026-01-23

A Study of SH006 Injection Combination Therapy in Patients With Advanced Solid Tumors

50 enrolled

Liver Neoplasms

NCT04377932 2026-01-21

Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

14 enrolled 12 charts

Liposarcoma, Liver Neoplasms, Wilms Tumor, Rhabdomyosarcoma, Endodermal Sinus Tumor, Rhabdoid Tumor

NCT05155189 2026-01-21

A Study to Evaluate Safety and Efficacy of Armored CAR-T Cell Injection C-CAR031 in Advanced Hepatocellular Carcinoma

72 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT07317505 2026-01-21

A Phase 1 Study of JMT108 in Participants With Advanced Solid Tumors

DermatologicGastrointestinal

270 enrolled

Liver Neoplasms, Melanoma, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT04658147 2025-12-18

Feasibility and Efficacy of Perioperative Nivolumab With or Without Relatlimab for Patients With Potentially Resectable Hepatocellular Carcinoma (HCC)

31 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT06478693 2025-12-18

A Study of MT-303 in Adults With Advanced or Metastatic GPC3-Expressing Cancers, Including HCC

70 enrolled

Simpson-Golabi-Behmel syndrome, Carcinoma, Hepatocellular, Liver Neoplasms

NCT02869217 2025-12-03

Study of TBI-1301 (NY-ESO-1 Specific TCR Gene Transduced Autologous T Lymphocytes) in Patients With Solid Tumors

DermatologicGastrointestinalGenitourinaryGynecologicSarcomaThoracic

22 enrolled

Urinary Bladder Neoplasms, Esophageal Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Ovarian Neoplasms, Sarcoma, Synovial

NCT05427396 2025-12-03

A Phase I Clinical Study of Recombinant Humanized Anti-BTLA Monoclonal Antibody (JS004) Injection Combined With Toripalimab Injection in Patients With Advanced Solid Tumors

Phase 1 Terminated

31 enrolled

GastrointestinalGynecologic

Esophageal Squamous Cell Carcinoma, Uterine Cervical Neoplasms, Liver Neoplasms

NCT04374877 2025-11-10

Study of CHS-388 (Formerly Known as SRF388) in Patients With Advanced Solid Tumors

GastrointestinalGenitourinaryThoracic

145 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Kidney Neoplasms, Liver Neoplasms, Neoplasms

NCT07224568 2025-11-04

INTERCEPT

Phase 1 Not yet recruiting

21 enrolled

GastrointestinalSarcoma

Carcinoma, Hepatocellular, Liposarcoma, Liver Neoplasms, Rhabdomyosarcoma, Endodermal Sinus Tumor

NCT05293496 2025-10-14

A Study of MGC018 in Combination With MGD019 in Participants With Advanced Solid Tumors

DermatologicGastrointestinalGenitourinaryGynecologic

31 enrolled

Carcinoma, Ovarian Epithelial, Carcinoma, Renal Cell, Liver Neoplasms, Melanoma, Carcinoma, Pancreatic Ductal, Prostatic Neoplasms, Castration-Resistant

NCT03993873 2025-10-01

SHIELD-1

95 enrolled

GastrointestinalThoracic

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms

NCT01218854 2025-09-22

A Comparison of Methods for Assisting Needle Angle Selection During Image-guided Tissue Biopsy

GastrointestinalGenitourinaryThoracic

17 enrolled

Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Neoplasms

NCT02932956 2025-09-19

GAP

10 enrolled

Liver Neoplasms

NCT06533332 2025-09-18

A Phase 1 Trial of ERX-315 in Participants With Advanced Solid Tumors

BreastGastrointestinalGynecologic

15 enrolled

Breast Neoplasms, Liver Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Endometrial Neoplasms

NCT04502082 2025-09-08

Study of ET140203 T Cells in Adults With Advanced Hepatocellular Carcinoma (ARYA-1)

Phase 1 Terminated

8 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT06873659 2025-09-03

SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors

96 enrolled

Liver Neoplasms, Stomach Neoplasms

NCT05701488 2025-09-02

SIRT With Tremelimumab and Durvalumab for Resectable HCC

20 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT06084299 2025-08-19

Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Advanced Liver Cancer

16 enrolled

Liver Neoplasms

NCT03132792 2025-08-15

AFPᶜ³³²T in Advanced HCC

45 enrolled

Liver Neoplasms, Neoplasm Metastasis

NCT03199586 2025-07-20

Clinical Trial of Metastasis Inhibitor NP-G2-044 in Patients With Advanced or Metastatic Treatment-Refractory Solid Tumor Malignancies

BreastGastrointestinalGenitourinaryGynecologicThoracic

23 enrolled

Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Liver Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms

NCT05788484 2025-06-15

A Study of CDX-585 in Patients With Advanced Malignancies

GastrointestinalGenitourinaryGynecologicHead & NeckThoracic

20 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Esophageal Neoplasms, Fallopian Tube Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT07001592 2025-06-03

RIOT3

18 enrolled

Esophageal Neoplasms, Liver Neoplasms, Stomach Neoplasms, Vaccinia

NCT03195699 2025-03-21

Oral STAT3 Inhibitor, TTI-101, in Patients With Advanced Cancers