NCT07527026 2026-04-14
A Single-arm Phase II Clinical Study of Camrelizumab Combined With Long-course Chemoradiotherapy for Total Neoadjuvant Therapy in Locally Advanced Low pMMR/MSS Rectal Cancer
Chinese PLA General Hospital
Phase 2 Recruiting
Clinical Trials
31 trialsNCT06281405 2026-04-03
TORCH-iTNT
Fudan University
Phase 2 Recruiting
NCT07469306 2026-03-13
Short-Course RT Plus CAPOX and Tislelizumab vs Long-Course CRT Plus Tislelizumab for Locally Advanced Rectal Cancer
Fujian Cancer Hospital
Phase 2 Not yet recruiting
NCT06493240 2025-11-25
NLCCRIT-LARC
Peking University People's Hospital
Phase 2 Completed
NCT07150949 2025-09-02
Long-course Chemoradiotherapy or Short-course Radiotherapy Combined With CAPOX, PD-1antibody, and COX-2 Inhibitor for MSS Locally Advanced Rectal Cancer (SERRAC)
Fudan University
Phase 2 Recruiting
NCT07057089 2025-08-14
Involved-field Radiotherapy-TNT Combined With PD-1 Inhibitor for pMMR Locally Advanced Rectal Cancer (Neo-Field I)
Hebei Medical University Fourth Hospital
Phase 2 Recruiting
NCT05253846 2025-06-10
ShorTrip
Gruppo Oncologico del Nord-Ovest
Phase 2 Active not recruiting
NCT06056804 2025-04-02
Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and Thymalfasin for pMMR/MSS Locally Advanced Mid-low Rectal Cancer
Beijing Friendship Hospital
Phase 2 Active not recruiting
NCT06840665 2025-02-21
MR-guided Adaptive Radiotherapy Combined With PD-1 Antibody and CAPOX for Locally Advanced Rectal Cancer
Fudan University
Phase 2 Recruiting
NCT06802666 2025-01-31
Short-course Radiotherapy Followed by AK112 and CAPOX as Neoadjuvant Therapy for Locally Advanced Rectal Cancer
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Phase 2 Recruiting
NCT04518280 2025-01-17
TORCH
Fudan University
Phase 2 Completed
NCT06760520 2025-01-08
Short-course Radiotherapy Followed by CAPOX and Ivonescimab for Locally Advanced Rectal Cancer
The First Affiliated Hospital of Zhengzhou University
Phase 2 Not yet recruiting
NCT05086627 2024-08-22
Short-course Radiotherapy Followed by Tislelizumab + CapeOX in the Treatment for Locally Advanced Rectal Cancer
Hebei Medical University Fourth Hospital
Phase 2 Completed
NCT06304987 2024-03-19
Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and PCSK9 Inhibitor for pMMR/MSS Locally Advanced Mid-low Rectal Cancer
Beijing Friendship Hospital
Phase 2 Not yet recruiting
NCT05980689 2024-02-07
Combination of AK104 and Neoadjuvant Chemoradiotherapy in pMMR/MSS Locally Advanced Rectal Cancer
Sun Yat-sen University
Phase 2 Unknown
NCT03503630 2024-01-31
Short-course Radiation Followed by mFOLFOX-6 Plus COMPOUND 2055269 for Locally-advanced Rectal Adenocarcinoma
American University of Beirut Medical Center
Phase 2 Unknown
NCT05245474 2024-01-10
Neoadjuvant Long-course Chemoradiation Plus PD-1 Blockade for Mid-low Locally Advanced Rectal Cancer
Beijing Friendship Hospital
Phase 2 Recruiting
NCT05998122 2023-08-18
Total Neoadjuvant Chemoradiotherapy Plus Anti-PD-1 in Subperitoneal Patients With Locally Advanced Rectal CancerPatients With Locally Advanced Rectal Cancer: A Prospective, Single Arm, Exploratory Study
The First Hospital of Jilin University
Phase 2 Not yet recruiting
NCT05845268 2023-05-06
Total Neoadjuvant Therapy Combined With Tislelizumab for Local Advanced of Middle and Low Rectal Cancer
Beijing Friendship Hospital
Phase 2 Unknown
NCT05300269 2022-07-29
SHR-1701 in Combination With Chemotherapy and Radiotherapy in Locally Advanced Rectal Cancer
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
Phase 2 Recruiting
NCT04989855 2021-08-04
Fruquintinib Plus PD-1 Antibody in pMMR / MSS Locally Advanced Rectal Cancer (LARC) With High Immune Score
Sun Yat-sen University
Phase 2 Unknown
NCT02167321 2021-04-22
Rectal Cancer, Adjuvant Chemotherapy, FOLFOX(5-fluorouracil/Leucovorin/Oxaliplatin), Total Mesorectal Excision
Yonsei University
Phase 2 Unknown
NCT04423965 2021-03-23
A Trial of Neoadjuvant mFOLFOXIRI Versus CRT in the EMVI Positive LARC
First Affiliated Hospital of Zhejiang University
Phase 2 Unknown
NCT04663763 2020-12-11
Neoadjuvant Short-course Radiotherapy Followed by the Combination of Immunotherapy and Chemotherapy in Locally Advanced Rectal Cancer
Zhejiang Cancer Hospital
Phase 2 Unknown
NCT04411524 2020-06-02
The Combination of Immunotherapy and Neoadjuvant Chemoradiotherapy in MSI-H Locally Advanced Rectal Cancer
Fudan University
Phase 2 Unknown
NCT04411537 2020-06-02
The Combination of Immunotherapy and Neoadjuvant Chemoradiotherapy in MSS Locally Advanced Rectal Cancer
Fudan University
Phase 2 Unknown
NCT04394598 2020-05-19
A Study of Chinese Herbal Compound Dendrobium Huoshanense Granules in NCRT for Patients With Locally Advanced Rectal Cancer
Fudan University
Phase 2 Unknown
NCT04170530 2019-11-20
Neoadjuvant mFOLFOXIRI Chemotherapy Alone for Extramural Vascular Invasion Positive Locally Advanced Rectal Cancer
First Affiliated Hospital of Zhejiang University
Phase 2 Unknown
NCT03702985 2019-01-23
Radiation-protection Effect of Amifostine in Locally Advanced Rectal Cancer
Fudan University
Phase 2 Unknown
NCT00931203 2016-05-04
Trial of Celecoxib With Preoperative Chemo- Radiation for Locally Advanced Rectal Cancer
National Health Research Institutes, Taiwan
Phase 2 Completed
NCT01899118 2013-07-15
Nimotuzumab in Combination With Chemoradiation in Patients With Locally Advanced Rectal Cancer
Zhejiang Cancer Hospital
Phase 2 Unknown