Clinical Trials

44 enrolled

Locally Advanced Rectal Cancer

NCT06281405 2026-04-03

TORCH-iTNT

192 enrolled

Phase NA Not yet recruiting

Locally Advanced Rectal Cancer

NCT07453173 2026-03-05

ONCO-RET

15 enrolled

Locally Advanced Rectal Cancer

NCT05412082 2026-02-06

SMART TNT

Phase 1 Recruiting

25 enrolled

Locally Advanced Rectal Cancer

NCT06493240 2025-11-25

NLCCRIT-LARC

30 enrolled

Locally Advanced Rectal Cancer

NCT07150949 2025-09-02

Long-course Chemoradiotherapy or Short-course Radiotherapy Combined With CAPOX, PD-1antibody, and COX-2 Inhibitor for MSS Locally Advanced Rectal Cancer (SERRAC)

138 enrolled

Locally Advanced Rectal Cancer

NCT02605265 2025-08-28

CinClare

Phase 3 Completed

356 enrolled

Locally Advanced Rectal Cancer

NCT07057089 2025-08-14

Involved-field Radiotherapy-TNT Combined With PD-1 Inhibitor for pMMR Locally Advanced Rectal Cancer (Neo-Field I)

90 enrolled

Phase 3 Not yet recruiting

Locally Advanced Rectal Cancer

NCT07074353 2025-07-25

CinClare-2

360 enrolled

Phase 2 Active not recruiting

Locally Advanced Rectal Cancer

NCT05253846 2025-06-10

ShorTrip

63 enrolled

Phase 2 Active not recruiting

Locally Advanced Rectal Cancer

NCT06056804 2025-04-02

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and Thymalfasin for pMMR/MSS Locally Advanced Mid-low Rectal Cancer

20 enrolled

Locally Advanced Rectal Cancer

NCT06894797 2025-03-25

Preoperative Chemoradiotherapy Combined With Consolidation or Induction NALIRIFOX in Rectal Cancer.

Phase NA Recruiting

68 enrolled

Locally Advanced Rectal Cancer

NCT06840665 2025-02-21

MR-guided Adaptive Radiotherapy Combined With PD-1 Antibody and CAPOX for Locally Advanced Rectal Cancer

46 enrolled

Locally Advanced Rectal Cancer

NCT06802666 2025-01-31

Short-course Radiotherapy Followed by AK112 and CAPOX as Neoadjuvant Therapy for Locally Advanced Rectal Cancer

45 enrolled

Locally Advanced Rectal Cancer

NCT04518280 2025-01-17

TORCH

130 enrolled

Phase 2 Not yet recruiting

Locally Advanced Rectal Cancer

NCT06760520 2025-01-08

Short-course Radiotherapy Followed by CAPOX and Ivonescimab for Locally Advanced Rectal Cancer

40 enrolled

Locally Advanced Rectal Cancer

NCT05086627 2024-08-22

Short-course Radiotherapy Followed by Tislelizumab + CapeOX in the Treatment for Locally Advanced Rectal Cancer

118 enrolled

Phase 2 Not yet recruiting

Locally Advanced Rectal Cancer

NCT06304987 2024-03-19

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and PCSK9 Inhibitor for pMMR/MSS Locally Advanced Mid-low Rectal Cancer

Locally Advanced Rectal Cancer

NCT05980689 2024-02-07

Combination of AK104 and Neoadjuvant Chemoradiotherapy in pMMR/MSS Locally Advanced Rectal Cancer

33 enrolled

Locally Advanced Rectal Cancer

NCT03503630 2024-01-31

Short-course Radiation Followed by mFOLFOX-6 Plus COMPOUND 2055269 for Locally-advanced Rectal Adenocarcinoma

44 enrolled

Locally Advanced Rectal Cancer

NCT05245474 2024-01-10

Neoadjuvant Long-course Chemoradiation Plus PD-1 Blockade for Mid-low Locally Advanced Rectal Cancer

186 enrolled

Locally Advanced Rectal Cancer

NCT03034473 2023-12-28

TransValid-A

200 enrolled

Phase 2 Not yet recruiting

Locally Advanced Rectal Cancer

NCT05998122 2023-08-18

Total Neoadjuvant Chemoradiotherapy Plus Anti-PD-1 in Subperitoneal Patients With Locally Advanced Rectal CancerPatients With Locally Advanced Rectal Cancer: A Prospective, Single Arm, Exploratory Study

45 enrolled

Locally Advanced Rectal Cancer

NCT05845268 2023-05-06

Total Neoadjuvant Therapy Combined With Tislelizumab for Local Advanced of Middle and Low Rectal Cancer

102 enrolled

Locally Advanced Rectal Cancer

NCT05079438 2021-10-15

Dendrobium Huoshanense Suppository in Rectal Cancer

Phase 3 Unknown

168 enrolled

Locally Advanced Rectal Cancer

NCT05079503 2021-10-15

Gut Microbiome and Its Immune Modulation in Locally Advanced Rectal Cancer

40 enrolled

Locally Advanced Rectal Cancer

NCT04989855 2021-08-04

Fruquintinib Plus PD-1 Antibody in pMMR / MSS Locally Advanced Rectal Cancer (LARC) With High Immune Score

48 enrolled

Locally Advanced Rectal Cancer

NCT02167321 2021-04-22

Rectal Cancer, Adjuvant Chemotherapy, FOLFOX(5-fluorouracil/Leucovorin/Oxaliplatin), Total Mesorectal Excision

90 enrolled

Locally Advanced Rectal Cancer

NCT04423965 2021-03-23

A Trial of Neoadjuvant mFOLFOXIRI Versus CRT in the EMVI Positive LARC

220 enrolled

Locally Advanced Rectal Cancer

NCT04663763 2020-12-11

Neoadjuvant Short-course Radiotherapy Followed by the Combination of Immunotherapy and Chemotherapy in Locally Advanced Rectal Cancer

40 enrolled

Locally Advanced Rectal Cancer

NCT04411524 2020-06-02

The Combination of Immunotherapy and Neoadjuvant Chemoradiotherapy in MSI-H Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

NCT04411537 2020-06-02

The Combination of Immunotherapy and Neoadjuvant Chemoradiotherapy in MSS Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

NCT04394598 2020-05-19

A Study of Chinese Herbal Compound Dendrobium Huoshanense Granules in NCRT for Patients With Locally Advanced Rectal Cancer

210 enrolled

Locally Advanced Rectal Cancer

NCT04170530 2019-11-20

Neoadjuvant mFOLFOXIRI Chemotherapy Alone for Extramural Vascular Invasion Positive Locally Advanced Rectal Cancer

51 enrolled

Locally Advanced Rectal Cancer

NCT02290574 2019-11-01

NEOTREAT

Phase NA Terminated

14 enrolled 7 charts

Locally Advanced Rectal Cancer

NCT03676517 2019-02-15

Evaluation of Efficacy, Quality of Life and Cost Effectiveness of Short-course Radiotherapy Followed by Capecitabine Plus Oxaliplatin chemotheRapy and TME for High-risk Rectal Cancer (ESCORT Trial)

31 enrolled

Locally Advanced Rectal Cancer

NCT03824899 2019-01-31

UGT1A1 Combined With Pharmacokinetics of SN-38 in CPT-11-based CRT in Patients With Advanced Rectal Cancer

100 enrolled

Locally Advanced Rectal Cancer

NCT03702985 2019-01-23

Radiation-protection Effect of Amifostine in Locally Advanced Rectal Cancer

160 enrolled

Locally Advanced Rectal Cancer

NCT00931203 2016-05-04

Trial of Celecoxib With Preoperative Chemo- Radiation for Locally Advanced Rectal Cancer

55 enrolled

Locally Advanced Rectal Cancer

NCT01899118 2013-07-15

Nimotuzumab in Combination With Chemoradiation in Patients With Locally Advanced Rectal Cancer