Clinical Trials

58 enrolled

Disease, Lung Diseases, Lung Neoplasms

NCT00534690 2026-05-15

REVOLU

88 enrolled

Lung Diseases, Lung Neoplasms

NCT05054725 2026-01-06

Combination Study of RMC-4630 and Sotorasib for NSCLC Subjects With KRASG12C Mutation After Failure of Prior Standard Therapies

Phase 2 Completed

47 enrolled 17 charts

Bronchial Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Hereditary Sensory and Autonomic Neuropathies, Respiratory Tract Diseases, Respiratory Tract Neoplasms

NCT04657120 2025-12-23

HYDRA

698 enrolled

Cardiovascular Diseases, Disease, Embolism, Lung Diseases, Neoplasms, Pulmonary Embolism, Respiratory Tract Diseases, Vascular Diseases, Embolism and Thrombosis

NCT04614129 2025-11-24

Lung Cancer Risk and Early Detection in Firefighters

734 enrolled

Lung Diseases, Lung Neoplasms

NCT06145750 2025-11-24

FIRSTLUNG

28 enrolled

Adenocarcinoma, Disease, Lung Diseases, Lung Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT06546839 2025-08-06

SPSIPB vs SAPB for Thoracoscopic Surgery

50 enrolled

Lung Diseases, Lung Neoplasms, Thoracic Diseases, Thoracic Neoplasms

NCT04702165 2025-07-29

Image - Navigated Resection of Lung Nodules

25 enrolled

Lung Diseases, Lung Neoplasms

NCT03613363 2025-06-06

Engineering Evaluation of the Helix Ventilator

LymphoidOther hematologic neoplasm

20 enrolled 9 charts

Lung Diseases, Respiration Disorders, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03037385 2025-05-31

ARROW

590 enrolled 58 charts 3 FDA

EndocrineGastrointestinalHead & NeckNETThoracic

Thyroid Cancer, Papillary, Adenocarcinoma, Adenocarcinoma, Papillary, Bronchial Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms, Thyroid Diseases, Thyroid Neoplasms, Colorectal Neoplasms, Neuroectodermal Tumors, Carcinoma, Medullary, Carcinoma, Neuroendocrine, Neuroendocrine Tumors, Multiple Endocrine Neoplasia Type 2a

NCT03767517 2025-05-23

A Culturally-Based Palliative Care Tele-consult Program for Rural Southern Elders

209 enrolled 16 charts

Genitourinary

Digestive System Diseases, Heart Diseases, Kidney Diseases, Lung Diseases, Neoplasms, Sepsis, Stroke

NCT04774952 2025-04-15

Dose Escalation of RMC-5552 Monotherapy in Relapsed/Refractory Solid Tumors

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

58 enrolled

Urinary Bladder Neoplasms, Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Esophageal Diseases, Esophageal Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Diseases, Lung Neoplasms, Melanoma, Neoplasms, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Hereditary Sensory and Autonomic Neuropathies, Ovarian Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Skin Neoplasms, Thoracic Neoplasms, Uterine Neoplasms, Neoplasms, Squamous Cell

NCT05795959 2025-02-12

Ensuring Precision-Medicine Delivery for Veterans With Lung Cancer

46 enrolled

Lung Diseases, Lung Neoplasms

NCT03721952 2025-02-07

FCS2

977 enrolled 38 charts

GenitourinaryThoracic

Brain Injuries, Cerebrovascular Disorders, Chronic Disease, Heart Failure, Kidney Failure, Chronic, Liver Cirrhosis, Lung Diseases, Lung Neoplasms, Multiple Organ Failure, Neoplasm Metastasis, Pulmonary Disease, Chronic Obstructive

NCT03612804 2024-10-08

PROACT

944 enrolled 16 charts

Tobacco Smoking, Smoking Reduction, Lung Diseases, Lung Neoplasms, Smoking Cessation, Tobacco Use

NCT03902782 2024-03-13

Erector Spinae Plane Block Versus Intercostal for VATS

100 enrolled

Lung Diseases, Lung Neoplasms

NCT02429479 2024-01-26

Preparing Family Caregivers to Make Medical Decisions for Their Loved Ones

285 enrolled

Genitourinary

Heart Failure, Kidney Diseases, Lung Diseases, Neoplasms

NCT04996693 2023-11-22

On Dose Efficiency of Modern CT-scanners in Chest Scans

958 enrolled

Aortic Valve Stenosis, Lung Diseases, Lung Neoplasms, Pneumonia, Pulmonary Embolism

NCT03989115 2023-06-26

Dose-Esc/Exp RMC4630 & Cobi in Relapsed/Refractory Solid Tumors & RMC4630& Osi in EGFR+ Locally Adv/Meta NSCLC

DermatologicGastrointestinalGenitourinaryGynecologicThoracic

113 enrolled 22 charts

Urinary Bladder Neoplasms, Bronchial Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Gastrointestinal Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Noonan Syndrome, Ovarian Neoplasms, Pancreatic Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Skin Neoplasms, Thoracic Neoplasms, Uterine Neoplasms, Colorectal Neoplasms, Neoplasms, Squamous Cell

NCT04666558 2022-10-04

PiONEeR

216 enrolled

Chronic Disease, Liver Diseases, Lung Diseases, Motor Activity, Neoplasms

NCT05257382 2022-07-27

Added Value of Cone Beam CT Guidance to Electromagnetic Navigation Bronchoscopy for the Diagnosis of Pulmonary Nodule.

49 enrolled

Lung Diseases, Lung Neoplasms

NCT02926768 2022-07-26

Phase I/II Study of CK-101 in NSCLC Patients and Other Advanced Solid Tumors

136 enrolled

Adenocarcinoma, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms

NCT02897778 2022-04-28

Cardiac Safety Study of Entinostat in Men and Women With Advanced Solid Tumors

BreastGastrointestinalGenitourinaryThoracic

30 enrolled

Breast Diseases, Breast Neoplasms, Bronchial Neoplasms, Carcinoma, Non-Small-Cell Lung, Digestive System Neoplasms, Endocrine Gland Neoplasms, Kidney Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms, Glandular and Epithelial, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT02909452 2022-01-25

Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

BreastGastrointestinalGenitourinaryThoracic

30 enrolled

Breast Diseases, Bronchial Neoplasms, Carcinoma, Non-Small-Cell Lung, Digestive System Neoplasms, Endocrine Gland Neoplasms, Kidney Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms, Glandular and Epithelial, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT01594398 2021-11-19

ENCORE110

14 enrolled

BreastThoracic

Breast Diseases, Breast Neoplasms, Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT01999985 2020-11-27

Phase I Trial of Afatinib (BIBW 2992) and Dasatinib in Non-small Cell Lung Cancer (NSCLC)

25 enrolled 10 charts

Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Pleural Diseases, Pleural Effusion, Pleural Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms, Pleural Effusion, Malignant

NCT04630743 2020-11-16

CoBeMEB

49 enrolled

Other

Dyspnea, Heart Failure, Lung Diseases, Neoplasms, Respiratory Insufficiency, Lung Diseases, Interstitial, Pulmonary Disease, Chronic Obstructive

NCT02259582 2020-09-09

DENALI

Phase 2 Completed

82 enrolled 10 charts

Carcinoma, Lung Diseases, Lung Neoplasms, Neoplasm Metastasis, Neoplasms

NCT03794414 2020-07-29

Positive End-expiratory Pressure (PEEP) in Predicting Fluid Responsiveness in Patients Undergoing One-lung Ventilation

40 enrolled

Lung Diseases, Lung Neoplasms

NCT03134872 2020-06-09

A Study of SHR-1210 in Combination With Pemetrexed and Carboplatin in Subjects With Non-squamous NSCLC

Phase 3 Completed

419 enrolled

Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT03704870 2020-05-01

Outcomes Following Omission of Daily Routine Chest Radiographs Following Pulmonary Resection

Phase 2 Completed

50 enrolled

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms

NCT03331588 2020-03-02

Comparison of Post-operative Pain and Quality of Life Between Subxiphoid and Intercostal VATS for Lung Cancer

Phase 3 Completed

200 enrolled

Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Pain, Thoracic Neoplasms

NCT00923520 2018-12-05

A Phase 1, Dose Escalation Study of the Safety, Tolerability, and Pharmacokinetics of Intravenous Dimethane Sulfonate (DMS612) in Advanced Malignancies

BreastGastrointestinalGenitourinaryLymphoidThoracic

60 enrolled

Breast Neoplasms, Carcinoma, Renal Cell, Colonic Neoplasms, Kidney Neoplasms, Lung Diseases, Lung Neoplasms, Lymphoma, Lymphoma, Non-Hodgkin, Neoplasms

NCT01672294 2017-04-17

Caregiver Outlook: An Intervention to Improve Caregiving in Serious Illness

286 enrolled 26 charts

Death, Heart Failure, Lung Diseases, Neoplasms

NCT00934778 2016-11-28

Minimally Invasive Endoscopy in Diffuse Lung Disease

100 enrolled

Lung Diseases, Lung Neoplasms

NCT00249964 2016-01-20

Combination Paclitaxel, Carboplatin and Temozolomide

15 enrolled

Lung Diseases, Neoplasms

NCT01039948 2015-04-08

A Phase 1b/2 Study in Asian Subjects With Non-Small Cell Lung Cancer

203 enrolled