Clinical Trials

47 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04929041 2026-04-13

Testing the Addition of Radiation Therapy to the Usual Treatment (Immunotherapy With or Without Chemotherapy) for Advanced Stage Non-small Cell Lung Cancer Patients Who Are PD-L1 Negative

Phase 2/3 Suspended

427 enrolled

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05198830 2026-04-13

Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin or Carboplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung Cancer

Phase 2 Recruiting

42 enrolled

Adenocarcinoma of Lung, Lung Neoplasms

NCT03410043 2026-04-06

Osimertinib, Surgery, and Radiation Therapy in Treating Patients With Stage IIIB or IV Non-small Cell Lung Cancer With EGFR Mutations, NORTHSTAR Study

173 enrolled

Phase 3 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03391869 2026-03-23

Nivolumab and Ipilimumab With or Without Local Consolidation Therapy in Treating Patients With Stage IV Non-Small Cell Lung Cancer

339 enrolled

Phase 1 Active not recruiting

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04902040 2026-03-18

Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies

Phase 1/2 Terminated

19 enrolled 11 charts

GenitourinaryThoracic

Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Lung Neoplasms

NCT04505267 2026-03-11

NBTXR3 and Radiation Therapy for the Treatment of Inoperable Recurrent Non-small Cell Lung Cancer

34 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06194448 2026-03-06

NEOLA

76 enrolled

Phase 1 Active not recruiting

Lung Neoplasms

NCT04013542 2026-03-05

Ipilimumab and Nivolumab in Combination With Radiation Therapy in Treating Patients With Stage 2-3 Non-small Lung Cancer

21 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05443971 2026-02-06

Durvalumab and Grid Therapy for Non-small Cell Lung Cancer in Progression During or After Treatment With PACIFIC Regimen

4 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04151940 2026-01-14

PET/CT Changes During Chemoimmunotherapy and Radiation Therapy in Patients With Stage IV Non-small Cell Lung Cancer

Phase NA Recruiting

80 enrolled

Phase 1/2 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04728230 2025-12-18

Olaparib and Durvalumab With Carboplatin, Etoposide, and/or Radiation Therapy for the Treatment of Extensive-Stage Small Cell Lung Cancer, PRIO Trial

63 enrolled

Phase 2 Not yet recruiting

Lung Neoplasms

NCT07258147 2025-12-02

Safety and Efficacy of Radiotherapy Combined With Immunochemotherapy in Pre-treated SCLC Patients With Liver Metastases

30 enrolled

Lung Neoplasms

NCT03801902 2025-09-23

Testing the Safety of Adding Either Monalizumab (IPH2201) or Oleclumab (MEDI9447) to Durvalumab (MEDI4736) Plus Standard Radiation Therapy for Locally Advanced Non-small Cell Lung Cancer (NSCLC), ARCHON-1 Trial

Phase 1 Completed

26 enrolled 17 charts

Phase 1/2 Active not recruiting

Lung Neoplasms

NCT01770418 2025-09-09

A Phase I/II Study of Hypofractionated Proton Therapy for Stage II-III Non-Small Cell Lung Cancer

32 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms

NCT05136846 2025-06-04

Papaverine in Combination With Chemoradiation for the Treatment of Stage II-III Non-small Cell Lung Cancer

Phase 1 Recruiting

28 enrolled

DermatologicGenitourinaryHead & NeckThoracic

Lung Neoplasms

NCT02318771 2025-05-15

Radiation Therapy and MK-3475 for Patients With Recurrent/Metastatic Head and Neck Cancer, Renal Cell Cancer, Melanoma, and Lung Cancer

Phase 1 Completed

41 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Renal Cell, Lung Neoplasms, Melanoma

NCT00838929 2025-05-04

Study of the Combination of Vorinostat and Radiation Therapy for the Treatment of Patients With Brain Metastases

Phase 1 Completed

17 enrolled 8 charts

BreastCNSThoracic

Brain Neoplasms, Breast Neoplasms, Lung Neoplasms

NCT05358691 2025-04-16

A Trial of AN0025 With Chemoradiation Therapy in Stage III NSCLC Participants

Phase 1 Withdrawn

Lung Neoplasms

NCT03035890 2025-04-01

Hypofractionated Radiation Therapy to Improve Immunotherapy Response in Non-Small Cell Lung Cancer

Phase NA Completed

35 enrolled 9 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04364048 2024-12-20

Durvalumab Followed by Chemoradiation and Consolidation Durvalumab for Stage III Non-small Cell Lung Cancer

Phase 2 Terminated

10 enrolled 10 charts

Lung Neoplasms

NCT01553942 2024-11-20

Afatinib With CT and RT for EGFR-Mutant NSCLC

19 enrolled

Lung Neoplasms

NCT05501665 2024-10-17

Split Course Adaptive Radiation Therapy With Pembrolizumab With/Without Chemotherapy for Treating Stage IV Lung Cancer

Phase 1/2 Recruiting

25 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06024941 2024-09-19

Re-Induce 2

Phase 2 Withdrawn

Lung Neoplasms

NCT04183218 2024-08-23

Characterizing Chemo-Radiotherapy Treatment-Related Cardiac Changes

Completed

24 enrolled

Lung Neoplasms

NCT05161533 2023-10-18

Hypofractionated Radiation Therapy After Durvalumab and Chemotherapy for the Treatment of Stage IV Extensive Stage Small Cell Lung Cancer, CASPIAN-RT Trial

Phase 2 Withdrawn

Lung Neoplasms

NCT04989283 2023-09-26

Testing the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy Treatment During Radiation Therapy for Superior Sulcus Non-small Cell Lung Cancer

Phase 2 Withdrawn

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03094884 2023-05-23

Pulsed Low Dose Rate Radiation With Concurrent Chemotherapy for Non-Small Cell Lung Cancer and Esophageal Cancer

Phase 1 Unknown

40 enrolled

GastrointestinalThoracic

Esophageal Neoplasms, Lung Neoplasms

NCT00193427 2022-03-03

Preoperative Therapy in Patients With Stages IB, II, IIIA, and Selected IIIB Patients With Non-Small Cell Lung Cancer

75 enrolled 7 charts

Lung Neoplasms

NCT01165658 2020-01-02

Study of Hypofractionated Proton Radiation Therapy in Thoracic Malignancies

BreastGenitourinarySarcomaThoracic

30 enrolled

EndocrineThoracic

Carcinoid Tumor, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Thymus Neoplasms, Small Cell Lung Carcinoma

NCT01091883 2019-03-13

Study Comparing the Safety and Effectiveness of Magnetic Resonance Guided Focused Ultrasound (MRgFUS) and External Beam Radiation (EBRT) for Treatment of Metastatic Bone Tumors and Multiple Myeloma

Phase NA Completed

60 enrolled

Cancer Pain, Bone Neoplasms, Breast Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Pain, Prostatic Neoplasms

NCT00745732 2018-11-14

Radiation Therapy (XRT) and ZD6474 in Non-Small Cell Lung Cancer (NSCLC)

3 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03637335 2018-08-20

METAXIOM

Phase 3 Terminated

26 enrolled

Head & NeckThoracic

Head and Neck Neoplasms, Lung Neoplasms, Neoplasm Metastasis

NCT00226590 2017-03-23

Induction Gemcitabine & Carboplatin Followed by Paclitaxel & Carboplatin +XRT in NSCLC

39 enrolled 9 charts

Carcinoma, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT01771289 2016-09-27

Neoadjuvant Concurrent Chemoradiation With Weekly Docetaxel/Cisplatin for Resectable IIIA-N2 NSCLC

Phase 2 Unknown

50 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00193375 2016-08-10

Irinotecan, Carboplatin and Radiation Therapy Followed by Bevacizumab in Limited Stage Small Cell Lung Cancer

60 enrolled 7 charts

Lung Neoplasms

NCT00227565 2016-07-06

Pemetrexed Disodium and Carboplatin in Treating Patients With Extensive-Stage Small Cell Lung Cancer

50 enrolled

Lung Neoplasms

NCT01851161 2015-09-18

Prone Patient Positioning in Reducing Tumor Motion and Improving Breathing Reproduction in Patients With Lung Cancer Undergoing Radiation Therapy

Terminated

23 enrolled

Lung Neoplasms

NCT00378404 2015-06-08

Phase I Trial of Docetaxel and Low-Dose Fractionated Radiation in the Treatment of Metastatic or Recurrent NSCLC

10 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Recurrence

NCT00238615 2015-05-12

Phase II Docetaxel / Carboplatin / XRT + Surgical Resection in Stage III NSCLC

Phase 2 Terminated

13 enrolled 9 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00864331 2013-08-07

Optimization of Treatment of Advanced Nonsmall Cell Lung Cancer Using Radiotherapy and Chemotherapy

Phase 3 Completed

251 enrolled