Clinical Trials

Lung Neoplasms, Carcinoma, Small Cell, Small Cell Lung Carcinoma

NCT02649673 2023-12-05

LCL161 Plus Topotecan for Patients With Relapsed/Refractory Small Cell Lung Cancer and Select Gynecologic Malignancies

Phase 1 Terminated

34 enrolled

GynecologicThoracic

Lung Neoplasms, Ovarian Neoplasms, Small Cell Lung Carcinoma

NCT02481830 2023-07-27

CheckMate331

569 enrolled 13 charts

Lung Neoplasms

NCT02963090 2023-02-15

Pembrolizumab vs Topotecan in Patients With Small Cell Lung Cancer

Phase 2 Terminated

9 enrolled 11 charts

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00025272 2021-09-09

Combination Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer

14 enrolled

Lung Neoplasms

NCT00547651 2019-11-06

AMR PH GL 2007 CL001 Phase 3 Trial in Patients With Small Cell Lung Cancer After Failure of First-Line Chemotherapy

637 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00287963 2018-05-17

Topotecan and Vinorelbine in Treating Patients With Recurrent Lung Cancer

18 enrolled

Adenocarcinoma of Lung, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Small Cell Lung Carcinoma

NCT00365547 2017-12-28

Topotecan and Bevacizumab in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer That Did Not Respond to Previous Systemic Chemotherapy

46 enrolled 11 charts

Adenocarcinoma of Lung, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00028925 2016-12-07

Combination Chemotherapy With or Without Filgrastim in Treating Patients With Previously Untreated Extensive-Stage Small Cell Lung Cancer

27 enrolled

Lung Neoplasms

NCT00003812 2016-07-20

Chemotherapy Plus Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

75 enrolled

Lung Neoplasms

NCT00033696 2016-07-19

Combination Chemotherapy and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

65 enrolled

Lung Neoplasms

NCT00003281 2016-07-13

Topotecan and Paclitaxel in Treating Patients With Recurrent or Refractory Small Cell Lung Cancer

84 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00004055 2016-07-13

Topotecan, Paclitaxel, and Filgrastim in Treating Patients With Previously Untreated Extensive-Stage Small Cell Lung Cancer

38 enrolled

Lung Neoplasms

NCT00006012 2016-07-06

Combination Chemotherapy and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

Phase 1/2 Completed

73 enrolled

Lung Neoplasms, Radiation Injuries, Drug-Related Side Effects and Adverse Reactions

NCT00087048 2016-03-22

Topotecan in Treating Patients With Recurrent Extensive-Stage Small Cell Lung Cancer

Phase 2 Terminated

1 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00466232 2015-12-16

Phase I Study of Weekly Topotecan in Combination With Sorafenib in Treatment of Relapsed Small Cell Lung Cancer

16 enrolled

Lung Neoplasms, Carcinoma, Small Cell

NCT00316186 2015-05-07

First-line Treatment Of Subjects With Extensive Disease Small Cell Lung Cancer With Weekly Hycamtin And Paraplatin

33 enrolled 10 charts

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00006374 2014-01-15

Combination Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer

Phase 2 Withdrawn

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00003917 2014-01-09

Topotecan in Treating Patients With Relapsed Small Cell Lung Cancer

4 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00041015 2014-01-09

Combination Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer

4 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00003943 2013-04-17

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Metastatic Cancer.

3 enrolled

Lung Neoplasms, Neoplasms, Unknown Primary

NCT00276276 2013-04-15

Active Symptom Control Alone Or In Combination With Oral Topotecan In Patients With Relapsed Resistant Small Cell Lung Cancer

141 enrolled

Lung Neoplasms, Recurrence, Small Cell Lung Carcinoma

NCT00004186 2013-04-12

Combination Chemotherapy in Treating Patients With Small Cell Lung Cancer

Phase 1/2 Completed

55 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00004137 2013-02-15

S9914: Combination Chemotherapy Plus Filgrastim in Untreated Extensive-Stage Small Cell Lung Cancer

88 enrolled

Lung Neoplasms

NCT00002537 2013-02-11

Radiation Therapy Plus Topotecan in Treating Patients With Non-small Cell Lung Cancer

20 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00002625 2013-02-11

Topotecan and Radiation Therapy in Treating Patients With Solid Tumors or Lymphoma

DermatologicGastrointestinalLymphoidOther hematologic neoplasmThoracic

5 enrolled

Burkitt Lymphoma, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Hodgkin Disease, Lung Neoplasms, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Small Cell Lung Carcinoma

NCT00305942 2013-01-31

Topotecan and Carboplatin in the First-Line Treatment of Patients With Extensive Stage Small Cell Lung Cancer

61 enrolled 9 charts

Lung Neoplasms, Carcinoma, Small Cell

NCT00294190 2012-12-10

Higher Dose Weekly Topotecan In The Treatment Of Patients With Extensive Stage Small-Cell Lung Cancer

38 enrolled

Lung Neoplasms, Carcinoma, Small Cell, Small Cell Lung Carcinoma

NCT00193388 2010-07-28

Weekly Topotecan in the Second-Line Treatment of Small Cell Lung Cancer

100 enrolled

Lung Neoplasms

NCT00193401 2010-07-28

Weekly Topotecan in the First-line Treatment of Elderly Patients With Small Cell Lung Cancer

40 enrolled

Lung Neoplasms

NCT00388089 2010-06-29

Bortezomib and Topotecan in Treating Patients With Advanced Solid Tumors

24 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00193245 2010-06-28

Oral Topotecan Versus Docetaxel in Second-Line Treatment of Non-Small Cell Lung Cancer

80 enrolled

Lung Neoplasms

NCT00322751 2010-01-07

Concurrent Radiotherapy With Weekly Topotecan for Primary Treatment of Inoperable Localized Non-small Cell Lung Cancer

10 enrolled

Lung Neoplasms

NCT00315861 2009-01-23

Topotecan in Combination With Pemetrexed in Patients With Advanced Malignancies

15 enrolled

GynecologicThoracic

Uterine Cervical Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms

NCT00502762 2008-03-12

Topotecan for Irinotecan-Refractory SCLC

Phase 2 Unknown