Announcements Trials
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Phase

Phase 2 3Phase 3 1Phase 1/2 1

Status

Terminated 4Completed 1

Sponsor Class

OTHER 4INDUSTRY 1

Study Type

Interventional 5

Sponsor

Cancer Type

Thoracic 5Other hematologic neoplasm 1Dermatologic 1CNS 1Breast 1

Conditions

Neoplasm Metastasis 5Lung Neoplasms 5Triple Negative Breast Neoplasms 4Breast Neoplasms 4Uterine Cervical Neoplasms 3Neoplasms 3Cholangiocarcinoma 3Carcinoma, Non-Small-Cell Lung 3Camurati-Engelmann Syndrome 3Squamous Cell Carcinoma of Head and Neck 2Sarcoma 2Melanoma 2Head and Neck Neoplasms 2Colonic Neoplasms 2Biliary Tract Neoplasms 2Vulvar Neoplasms 1Vaginal Neoplasms 1Urinary Bladder Neoplasms 1Tertiary Lymphoid Structures 1Recurrence 1Rectal Neoplasms 1Prostatic Neoplasms 1Penile Neoplasms 1Pancreatic Neoplasms 1Oropharyngeal Neoplasms 1Neoplasms, Germ Cell and Embryonal 1Nasopharyngeal Carcinoma 1Microsatellite Instability 1Metastatic Solid Tumors 1Mesothelioma, Malignant 1

Interventions

Carboplatin 340Cisplatin 238Paclitaxel 203Radiotherapy 195Pemetrexed 187Docetaxel 169Gemcitabine 157pembrolizumab 141Erlotinib Hydrochloride 107Etoposide 99Magnetic Resonance Spectroscopy 93Bevacizumab 91Specimen Handling 76Nivolumab 73Radiosurgery 72durvalumab 69Vinorelbine 54osimertinib 53Gefitinib 49Drug Therapy 49atezolizumab 42Irinotecan 42Radiation 40Topotecan 39Biopsy 39Standard of Care 38Cyclophosphamide 38Cetuximab 35Blood Specimen Collection 33Taxes 32

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Interventional × Lung Neoplasms × bintrafusp alfa protein, human × Clear all
NCT04789668 2026-03-18

Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases

M.D. Anderson Cancer Center

Phase 1/2 Terminated
8 enrolled 13 charts
BreastCNSDermatologicOther hematologic neoplasmThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Hematologic Neoplasms, Triple Negative Breast Neoplasms

NCT05061823 2026-02-02

Bintrafusp Alfa Program Rollover Study

EMD Serono

Phase 3 Completed
22 enrolled 11 charts
Thoracic

Lung Neoplasms, Neoplasms

NCT04396535 2025-11-17

Docetaxel With or Without Bintrafusp Alfa for the Treatment of Advanced Non-small Cell Lung Cancer

Mayo Clinic

Phase 2 Terminated
10 enrolled 17 charts
Thoracic

Lung Neoplasms

NCT04971187 2023-08-01

Bintrafusp Alfa With Chemotherapy for Tyrosine Kinase Inhibitor-Resistant EGFR-Mutant Non-small Cell Lung Cancer

M.D. Anderson Cancer Center

Phase 2 Terminated
3 enrolled 8 charts
Thoracic

Lung Neoplasms

NCT04560686 2022-07-28

Bintrafusp Alfa Before Surgery for the Treatment of Untreated Resectable Non-small Cell Lung Cancer

M.D. Anderson Cancer Center

Phase 2 Terminated
2 enrolled 7 charts
Thoracic

Lung Neoplasms

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