Development of a Biologic Specimen Bank for the Study of Early Markers of Lung Cancer Among Tin Miners in Yunnan, China
Completed
9,759 enrolled
Genetic Analysis of Blood and Tissue Samples From Patients With Advanced Cancer, Moonshot Study
Completed
64 enrolled
Mobile Sensor Technologies to Assess General Symptomology of People With Cancer
Completed
49 enrolled
Testing the Safety of Adding Either Monalizumab (IPH2201) or Oleclumab (MEDI9447) to Durvalumab (MEDI4736) Plus Standard Radiation Therapy for Locally Advanced Non-small Cell Lung Cancer (NSCLC), ARCHON-1 Trial
Phase 1 Completed
26 enrolled 17 charts
A Comparison of Methods for Assisting Needle Angle Selection During Image-guided Tissue Biopsy
Phase 1 Completed
17 enrolled
Trial of EP0057, a Nanoparticle Camptothecin With Olaparib in People With Relapsed/Refractory Small Cell Lung Cancer
Phase 1/2 Completed
45 enrolled 30 charts
M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers
Phase 1/2 Completed
37 enrolled 19 charts
Eligibility Screening for the NIH Intramural Research Program Clinical Protocols
Completed
19,522 enrolled
Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction
Phase 1 Completed
37 enrolled
Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer
Phase 1 Completed
58 enrolled 17 charts
Collection of Blood, Bone Marrow, Tumor, or Tissue Samples From Patients With Cancer to Study Drug Resistance
Completed
86 enrolled
Retrospective Analysis of a Drug-Metabolizing Genotype in Cancer Patients and Correlation With Pharmacokinetic and Pharmacodynamics Data
Completed
484 enrolled
Local Ablative Therapy for Treatment of Oligoprogressive, EGFR-Mutated, Non-Small Cell Lung Cancer After Treatment With Osimertinib
Phase 2 Completed
37 enrolled 23 charts
A Nested Case-Control Study of Lung Cancer and Diesel Exhaust Among Non-Metal Miners
Completed
1,187 enrolled
Vaccine Therapy in Treating Patients With Colon, Pancreatic, or Lung Cancer
Phase 1 Completed
FR901228 in Treating Patients With Refractory or Progressive Small Cell Lung Cancer or Non-small Cell Lung Cancer
Phase 2 Completed
Vaccine Therapy in Treating Patients With Metastatic Cancer
Phase 1 Completed
Iloprost in Preventing Lung Cancer in Former Smokers
Phase 1 Completed
34 enrolled
A Case-Cohort Study of Hematopoietic Malignancies and Related Disorders and Lung Cancer in Benzene-Exposed Workers in China
Completed
3,260 enrolled
Safety and Tolerability of a Modified Vaccinia Ankara (MVA)-Based Vaccine Modified to Express Brachyury and T-cell Costimulatory Molecules (MVA-Brachyury-TRICOM)
Phase 1 Completed
38 enrolled 20 charts
Smoky Coal Exposure, Genetic Susceptibility, and Lung Cancer in Non-Smoking Women in China
Completed
3,720 enrolled
Multi-Targeted Recombinant Ad5 (CEA/MUC1/Brachyury) Based Immunotherapy Vaccine Regimen in People With Advanced Cancer
Phase 1 Completed
11 enrolled 18 charts
A Prospective Cohort Study of Occupational Exposures and Cancer Risk Among Women
Completed
75,366 enrolled
Study of Health Effects of Cosmetic Breast Augmentation
Completed
17,424 enrolled
Genetic Epidemiology of Lung Cancer and Smoking
Completed
4,429 enrolled
Cigarette Smoking and Oral Microbiota
Completed
50 enrolled
DNA Repair, p53 and Apoptosis Phenotypes in Lung Cancer
Completed
5,625 enrolled
Genetic Epidemiology of Lung Cancer
Completed
6,356 enrolled
Prevention of Tumor Spread Due to Lung Cancer Surgery
Completed
41 enrolled
A Multi-Histology Phase II Study of 5-Fluoro-2'-Deoxycytidine With Tetrahydrouridine (FdCyd + THU)
Phase 2 Completed
95 enrolled 15 charts
Testing a Spanish Version of a Patient Toxicity Questionnaire
Completed
112 enrolled
An Open Label Phase I Study to Eval the Safety and Tolerability of a Vaccine (GI-6207) Consisting of Whole, Heat-killed Recombinant Saccharomyces Cerevisiae (Yeast) Genetically Modified to Express CEA Protein in Adults With Metastatic CEA-expressing ...
Phase 1 Completed
25 enrolled
Prospective Analysis of Genotypes in Adults Undergoing Therapy for Lung Cancer
Completed
546 enrolled
Phase I Study of Gene Induction Mediated by Sequential Decitabine/Depsipeptide Infusion With or Without Concurrent Celecoxib in Subjects With Pulmonary and Pleural Malignancies
Phase 1 Completed
34 enrolled
A Phase 1, Dose Escalation Study of the Safety, Tolerability, and Pharmacokinetics of Intravenous Dimethane Sulfonate (DMS612) in Advanced Malignancies
Phase 1 Completed
60 enrolled
Intermittent or Continuous Acetylsalicylic Acid and Gene Expression in the Nasal Tissue of Current Smokers
Phase 2 Completed
54 enrolled 15 charts
Effect of Talactoferrin in Adults With Non-Small Cell Lung Cancer
Phase 1 Completed
10 enrolled
Effect of Lung Cancer Diagnoses on Family Behaviors
Completed
507 enrolled
Construction and Use of Lung Tumor Microarray for the Analysis of Gene Expression in Lung Cancer
Completed
500 enrolled
Impact of Lung Cancer Diagnosis on Relatives' Understanding of Genetic Risk and Receptivity to Quit Smoking
Completed
757 enrolled
African American Families and Lung Cancer Study
Completed
400 enrolled
HIV Infection and Tobacco Use Among Injection Drug Users in Baltimore, Maryland: A Pilot Study of Biomarkers
Completed
A Phase I Trial of SS1 (dsFv) PE38 With Paclitaxel, Carboplatin, and Bevacizumab in Subjects With Unresectable Non-Small Cell Lung Adenocarcinoma
Phase 1 Completed
2 enrolled
Randomized Phase II Study of AZD6244 (Mitogen-activated Protein Kinase Inhibitor) MEK-Inhibitor With Erlotinib in KRAS Wild Type Advanced Non-Small Cell Lung Cancer (NSCLC) and a Randomized Phase II Study of AZD6244 With Erlotinib in Mutant KRAS Adva...
Phase 2 Completed
89 enrolled 28 charts
Cognitive Testing of Tobacco Use Measurement Items for Administration With Cancer Patients and Survivors
Completed
30 enrolled 13 charts
Budesonide in Treating Patients With Lung Nodules at High Risk of Developing Lung Cancer
Phase 2 Completed
225 enrolled 10 charts
Lung Screening Study
Phase NA Completed
EF5 in Assessing Tumor Response to Anticancer Therapy in Patients With Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer
Phase 2 Completed
60 enrolled
Immunotoxin Therapy in Treating Patients With Advanced Cancer
Phase 1 Completed
Immunotoxin Therapy in Treating Patients With Advanced Solid Tumors
Phase 1 Completed