Clinical Trials

30 enrolled

Lung Neoplasms

NCT06503744 2026-04-13

Transthoracic vs Transbronchial Radiofrequency Ablation for Lung Cancer

110 enrolled

Lung Neoplasms

NCT06660407 2026-04-13

Grid Radiation Therapy for the Treatment of Stage IV Non-Small Cell Lung Cancer

20 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06909201 2026-04-13

Hyperpolarized Xenon-129 Magnetic Resonance Imaging in Lung Cancer Patients Receiving Radiation Therapy for Investigating Radiation-response and Toxicity

70 enrolled

Lung Neoplasms

NCT07104630 2026-04-13

Pulmonary Rehabilitation in Advanced Lung Cancer Survivors

85 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT07524114 2026-04-13

SHERLOCK

BreastDermatologicGastrointestinalHead & NeckThoracic

7,000 enrolled

Breast Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Unknown Primary, Urogenital Neoplasms, Neoplasm, Residual

NCT06810375 2026-04-09

Erector Spinae Versus Intercostal Nerve Blocks With Liposomal Bupivacaine for Analgesia in Thoracic Surgery

120 enrolled

Lung Neoplasms

NCT07339059 2026-04-09

Phase II Study of Sacituzumab Govitecan With Atezolizumab/Durvalumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer

35 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT04919382 2026-04-08

Temozolomide and Atezolizumab for Subsequent Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer

56 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT05281237 2026-04-08

Avecure Flexible Microwave Ablation Probe For Lung Nodules

10 enrolled

Lung Neoplasms

NCT05987644 2026-04-08

DURABLE

Phase 1/2 Recruiting

56 enrolled

CNSThoracic

Brain Neoplasms, Lung Neoplasms

NCT05334069 2026-04-07

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

BreastDermatologicGastrointestinalGenitourinaryHead & NeckLymphoidMyeloidOther hematologic neoplasmSarcomaThoracic

2,000 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Esophageal Neoplasms, Lung Neoplasms, Melanoma, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT06079970 2026-04-07

CLEVER

208 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06080061 2026-04-07

Personalized Accelerated ChEmoRadiation (PACER) for Lung Cancer

45 enrolled

Lung Neoplasms

NCT06632327 2026-04-07

Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer

1,100 enrolled

Lung Neoplasms

NCT07514754 2026-04-07

GALENOS 2

52 enrolled

Head & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Lung Neoplasms

NCT06495125 2026-04-06

Defactinib, Avutometinib and Nivolumab for the Treatment of Anti-PD1 Refractory LKB1-Mutant Advanced Non-Small Cell Lung Cancer

50 enrolled

Adenocarcinoma of Lung, Lung Neoplasms

NCT07458425 2026-04-06

The SENTINL-1 Study: Evaluating Patient-Reported Outcomes of AI-Inferred Lung Cancer Risk

400 enrolled

Lung Neoplasms

NCT07511413 2026-04-06

GALENOS 1

110 enrolled

Head & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Lung Neoplasms, Sarcopenia

NCT04804644 2026-04-03

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

200 enrolled

CNSThoracic

Brain Neoplasms, Lung Neoplasms, Small Cell Lung Carcinoma

NCT05624996 2026-04-03

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

474 enrolled

Lung Neoplasms

NCT06249282 2026-04-03

Carfilzomib in Combination With Sotorasib for the Treatment of Patients With KRAS G12C Mutated Advanced or Metastatic Non-small Cell Lung Cancer

15 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06500455 2026-04-03

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

BreastCNSDermatologicGenitourinaryThoracic

269 enrolled

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Lung Neoplasms, Melanoma, Neoplasm Metastasis

NCT06500481 2026-04-03

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

115 enrolled

BreastCNSThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Meningeal Carcinomatosis

NCT07509333 2026-04-03

MDT-Based Umbrella Decision Model for Geriatric Lung Cancer Patients

2,000 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Small Cell Lung Carcinoma

NCT07510724 2026-04-03

IKF-ReWoLuTe

240 enrolled

Carcinoma, Non-Small-Cell Lung, Disease, Lung Neoplasms, Small Cell Lung Carcinoma

NCT03025256 2026-04-02

Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease

75 enrolled

DermatologicThoracic

Uveal Melanoma, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Melanoma, Meningeal Neoplasms, Nevus

NCT05746325 2026-04-02

Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast or Lung Cancer

5 enrolled

BreastCNSThoracic

Breast Neoplasms, Lung Neoplasms, Meningeal Carcinomatosis

NCT07140315 2026-04-02

DK222 Study at Hopkins

6 enrolled

GenitourinaryThoracic

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT07460999 2026-04-02

Sing-a-Lung 2

100 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pulmonary Disease, Chronic Obstructive

NCT04762199 2026-03-31

MRX-2843 and Osimertinib for the Treatment of Advanced EGFR Mutant Non-small Cell Lung Cancer

69 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05681780 2026-03-31

Clinical Trial of CD40L-Augmented TIL for Patients With EGFR, ALK, ROS1 or HER2-Driven NSCLC

20 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05977803 2026-03-31

ACROP

60 enrolled

CNSThoracic

Brain Neoplasms, Lung Neoplasms, Neoplasm Metastasis

NCT07504367 2026-03-31

Large Language Models Assist in Tumor MDT

BreastGastrointestinalThoracic

60 enrolled

Breast Neoplasms, Liver Neoplasms, Lung Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT05195385 2026-03-30

CASCADE

2,635 enrolled

Lung Neoplasms

NCT05578326 2026-03-30

Study of Trilaciclib and Lurbinectidin

30 enrolled

Lung Neoplasms, Neutropenia, Small Cell Lung Carcinoma

NCT07134660 2026-03-30

Thoracic Surgery Intercostal Block Trial With Liposomal vs. Hydrochloride Bupivacaine

210 enrolled

Lung Neoplasms, Pain, Postoperative

NCT05142033 2026-03-27

ASAP

BreastCNSGastrointestinalGynecologicOther hematologic neoplasmThoracic

25,000 enrolled

Breast Neoplasms, Colonic Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Neoplasms, Ovarian Neoplasms, Central Nervous System Neoplasms, Endometrial Neoplasms, Hematologic Neoplasms

NCT06538038 2026-03-27

Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

538 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06869447 2026-03-27

New York Better Breathing Study

100 enrolled