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Phase

Phase 4 1Phase 1/2 1

Status

Active not recruiting 4Recruiting 3Completed 1

Sponsor Class

OTHER 3

Study Type

Interventional 2Observational 1

Sponsor

Cancer Type

Myeloid 3Lymphoid 3

Conditions

Breast Neoplasms 1230Neoplasms 1040Carcinoma, Non-Small-Cell Lung 757Prostatic Neoplasms 697Colorectal Neoplasms 598Lung Neoplasms 578Pancreatic Neoplasms 403Leukemia, Myeloid, Acute 399Neoplasm Metastasis 391Ovarian Neoplasms 373Multiple Myeloma 373Stomach Neoplasms 319Carcinoma, Hepatocellular 304Melanoma 284Brain Neoplasms 281Recurrence 280Squamous Cell Carcinoma of Head and Neck 269Head and Neck Neoplasms 240Endometrial Neoplasms 236Glioblastoma 235Triple Negative Breast Neoplasms 230Precursor Cell Lymphoblastic Leukemia-Lymphoma 226Lymphoma 226Uterine Cervical Neoplasms 225Sarcoma 202Hematologic Neoplasms 201Urinary Bladder Neoplasms 197Esophageal Neoplasms 192Carcinoma, Renal Cell 191Lymphoma, Non-Hodgkin 177

Interventions

zanubrutinib 1pegaspargase 1Rituximab 1Methylprednisolone 1Etoposide 1Asparaginase 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Recruiting × Lymphohistiocytosis, Hemophagocytic × 1 year × Clear all
NCT07525466 2026-04-13

Combination of Mitoxantrone Liposome and Etoposide, Dexamethasone, Pegaspargase and Golidocitinib (MEPL-G) in the Treatment of NK/T-cell Lymphoma Associated Hemophagocytic Lymphohistiocytosis (NKTCL-HLH)

Beijing Tongren Hospital

Phase 1/2 Recruiting
25 enrolled
LymphoidMyeloid

Lymphohistiocytosis, Hemophagocytic, Lymphoma, Extranodal NK-T-Cell

NCT05898477 2026-01-22

Describing Treatment Outcomes and Responses in Lymphoma-associated Hemophagocytic Lymphohistiocytosis

University of Alabama at Birmingham

Recruiting
2,000 enrolled
LymphoidMyeloid

Lymphoma, Lymphohistiocytosis, Hemophagocytic

NCT07270835 2025-12-08

Zanubrutinib Combined With Rituximab in the Treatment of Secondary HLH in B-cell Lymphoma

The First Affiliated Hospital of Soochow University

Phase 4 Recruiting
40 enrolled
LymphoidMyeloid

Lymphoma, B-Cell, Lymphohistiocytosis, Hemophagocytic

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