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Phase

Phase 1/2 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Myeloid 1Lymphoid 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 84Leukemia 49Lymphoma 21Burkitt Lymphoma 19Leukemia, Biphenotypic, Acute 14Leukemia, Myeloid, Acute 10Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 8Lymphoma, Extranodal NK-T-Cell 7Recurrence 6Lymphoma, Non-Hodgkin 6Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 4Myelodysplastic Syndromes 4Dendritic Cell Sarcoma, Interdigitating 4Neoplasm, Residual 3Down Syndrome 3Anemia, Refractory, with Excess of Blasts 3Myeloproliferative Disorders 2Lymphoma, Large-Cell, Immunoblastic 2Lymphoma, Large B-Cell, Diffuse 2Leukemia, Myelomonocytic, Chronic 2Leukemia, Monocytic, Acute 2Leukemia, Erythroblastic, Acute 2Leukemia, Eosinophilic, Acute 2Anemia, Refractory 2Thrombocytopenia 1Sarcoma, Myeloid 1Pancreatic Neoplasms 1Neutropenia 1Neoplasms 1Nasopharyngeal Carcinoma 1

Interventions

Etoposide 7pegaspargase 5Methylprednisolone 4Dexamethasone 4Cyclophosphamide 3Alemtuzumab 3Gemcitabine 2Emapalumab 2Doxorubicin 2zanubrutinib 1tocilizumab 1sintilimab 1ruxolitinib 1fludarabine phosphate 1fludarabine 1Whole-Body Irradiation 1Vincristine 1Thiotepa 1Tacrolimus 1Rituximab 1Prednisone 1N-(2-amino-5-fluorobenzyl)-4-(N-(pyridine-3-acrylyl)aminomethyl)benzamide 1Methylprednisolone Hemisuccinate 1Methotrexate 1Melphalan 1EPOCH protocol 1Cytarabine 1Cisplatin 1Calcium Dobesilate 1Busulfan 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Interventional × Lymphohistiocytosis, Hemophagocytic × Asparaginase × Clear all
NCT07525466 2026-04-13

Combination of Mitoxantrone Liposome and Etoposide, Dexamethasone, Pegaspargase and Golidocitinib (MEPL-G) in the Treatment of NK/T-cell Lymphoma Associated Hemophagocytic Lymphohistiocytosis (NKTCL-HLH)

Beijing Tongren Hospital

Phase 1/2 Recruiting
25 enrolled
LymphoidMyeloid

Lymphohistiocytosis, Hemophagocytic, Lymphoma, Extranodal NK-T-Cell

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