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Phase

Phase 3 2Phase 4 1Phase 2 1Phase 1/2 1

Status

Unknown 4Recruiting 1

Sponsor Class

OTHER 5

Study Type

Interventional 5

Sponsor

Cancer Type

Myeloid 5Lymphoid 3

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 90Leukemia 45Lymphoma, Extranodal NK-T-Cell 24Burkitt Lymphoma 19Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 12Lymphoma 12Recurrence 9Leukemia, Biphenotypic, Acute 9Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 6Lymphohistiocytosis, Hemophagocytic 5Leukemia, T-Cell 4Neoplasms 3Lymphoma, T-Cell 3Leukemia, Myeloid, Acute 3Down Syndrome 3Neoplasm, Residual 2Lymphoma, Non-Hodgkin 2Epstein-Barr Virus Infections 2Ovarian Neoplasms 1Neoplasms, Plasma Cell 1Multiple Myeloma 1Mucositis 1Lymphoproliferative Disorders 1Leukemia, Myelogenous, Chronic, BCR-ABL Positive 1Leukemia, Lymphoid 1Leukemia, B-Cell 1Immunoproliferative Disorders 1Hodgkin Disease 1Hematologic Neoplasms 1Fallopian Tube Neoplasms 1

Interventions

Etoposide 7pegaspargase 5Methylprednisolone 4Dexamethasone 4Cyclophosphamide 3Alemtuzumab 3Gemcitabine 2Flow Cytometry 2Emapalumab 2Doxorubicin 2zanubrutinib 1tocilizumab 1sintilimab 1ruxolitinib 1fludarabine phosphate 1fludarabine 1Whole-Body Irradiation 1Vincristine 1Thiotepa 1Th1-Th2 Balance 1Tacrolimus 1Rituximab 1Prednisone 1Polymerase Chain Reaction 1N-(2-amino-5-fluorobenzyl)-4-(N-(pyridine-3-acrylyl)aminomethyl)benzamide 1Methylprednisolone Hemisuccinate 1Methotrexate 1Melphalan 1In Situ Hybridization 1Immunohistochemistry 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Lymphohistiocytosis, Hemophagocytic × pegaspargase × Clear all
NCT07525466 2026-04-13

Combination of Mitoxantrone Liposome and Etoposide, Dexamethasone, Pegaspargase and Golidocitinib (MEPL-G) in the Treatment of NK/T-cell Lymphoma Associated Hemophagocytic Lymphohistiocytosis (NKTCL-HLH)

Beijing Tongren Hospital

Phase 1/2 Recruiting
25 enrolled
LymphoidMyeloid

Lymphohistiocytosis, Hemophagocytic, Lymphoma, Extranodal NK-T-Cell

NCT04999878 2021-08-11

RUE-DDGP

Zhengzhou University

Phase 4 Unknown
30 enrolled
LymphoidMyeloid

Lymphohistiocytosis, Hemophagocytic, Lymphoma, Extranodal NK-T-Cell

NCT04405375 2020-05-28

GPED Regimen for Relapsed/Refractory or Advanced ENKTCL

Beijing Tongren Hospital

Phase 2 Unknown
29 enrolled
LymphoidMyeloid

Lymphohistiocytosis, Hemophagocytic, Lymphoma, Extranodal NK-T-Cell

NCT02912702 2016-09-23

L-DEP as an Initial Treatment for EBV-HLH

Beijing Friendship Hospital

Phase 3 Unknown
120 enrolled
Myeloid

Epstein-Barr Virus Infections, Lymphohistiocytosis, Hemophagocytic

NCT02631109 2016-08-04

L-DEP Regimen as a Salvage Therapy for Refractory Epstein Barr Virus-induced Hemophagocytic Lymphohistiocytosis

Beijing Friendship Hospital

Phase 3 Unknown
120 enrolled
Myeloid

Epstein-Barr Virus Infections, Lymphohistiocytosis, Hemophagocytic

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