Announcements Trials
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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Lymphoid 1

Conditions

Sarcoma 5Rhabdoid Tumor 4Lymphoma, Large B-Cell, Diffuse 4Lymphoma, Follicular 4Sarcoma, Synovial 3Lymphoma, Non-Hodgkin 3Lymphoma, B-Cell 3Wilms Tumor 2Sarcoma, Ewing 2Rhabdomyosarcoma 2Recurrence 2Osteosarcoma 2Neuroectodermal Tumors, Primitive, Peripheral 2Neuroblastoma 2Mesothelioma 2Medulloblastoma 2Histiocytosis, Langerhans-Cell 2Hepatoblastoma 2Glioma 2Ependymoma 2Central Nervous System Neoplasms 2Xanthogranuloma, Juvenile 1Prostatic Neoplasms 1Ovarian Neoplasms 1Neurofibrosarcoma 1Nerve Sheath Neoplasms 1Lymphoma, Mantle-Cell 1Lymphoma, B-Cell, Marginal Zone 1Inhibition, Psychological 1Hodgkin Disease 1

Interventions

Rituximab 67Cyclophosphamide 52fludarabine phosphate 44Whole-Body Irradiation 36Mycophenolic Acid 33Peripheral Blood Stem Cell Transplantation 29Tacrolimus 27Busulfan 24Cyclosporine 21Antilymphocyte Serum 21Melphalan 18Filgrastim 16Etoposide 15Methotrexate 14Radiotherapy 12Lenalidomide 12Cord Blood Stem Cell Transplantation 12fludarabine 10Sirolimus 10Granulocyte Colony-Stimulating Factor 10Dexamethasone 9Bendamustine Hydrochloride 9Prednisone 8Bortezomib 8thymoglobulin 7idelalisib 7Flow Cytometry 7Calcium Dobesilate 7ibritumomab tiuxetan 6Methylprednisolone 6

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Has results × Lymphoma, B-Cell, Marginal Zone × tazemetostat × Clear all
NCT03028103 2023-06-26

Open-Label, Multicenter, Two-Part, Phase 1 Study to Characterize Effects of a Moderate CYP3A Inhibitor on PK of Tazemetostat, Effects of Tazemetostat on PK of CYP2C8 and CYP2C19 Substrates, and Effect of Increased Gastric pH on PK of Tazemetostat in B-cell Lymphoma or Advanced Solid Tumor Patients

Ipsen

Phase 1 Completed
32 enrolled 30 charts
Lymphoid

Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell

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