Announcements Trials
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Phase

Phase 3 2Phase 4 1Phase 2 1Phase 1 1

Status

Active not recruiting 3Recruiting 1Completed 1

Sponsor Class

INDUSTRY 4OTHER 1

Study Type

Interventional 5

Sponsor

Cancer Type

Lymphoid 5Other hematologic neoplasm 2

Conditions

Leukemia, Lymphocytic, Chronic, B-Cell 45Lymphoma, Mantle-Cell 23Lymphoma, Non-Hodgkin 15Lymphoma, Large B-Cell, Diffuse 14Lymphoma, Follicular 10Waldenstrom Macroglobulinemia 9Lymphoma 9Lymphoma, B-Cell, Marginal Zone 7Leukemia 7Recurrence 6Neoplasms 6Lymphoma, B-Cell 5Leukemia, B-Cell 5Bronchiolitis Obliterans Syndrome 5Multiple Myeloma 3Leukemia, Prolymphocytic 3Leukemia, Lymphoid 3Hematologic Diseases 3Graft vs Host Disease 3Burkitt Lymphoma 3Melanoma 2Leukemia, Hairy Cell 2Hematologic Neoplasms 2Glioblastoma 2Brain Neoplasms 2Squamous Cell Carcinoma of Head and Neck 1Prostatic Neoplasms, Castration-Resistant 1Primary Central Nervous System Lymphoma (PCNSL) 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Neurologic Manifestations 1

Interventions

Cyclophosphamide 49Rituximab 32fludarabine 30Doxorubicin 14Specimen Handling 13Magnetic Resonance Spectroscopy 13Vincristine 12Prednisone 12fludarabine phosphate 11pirtobrutinib 10Etoposide 10Bendamustine Hydrochloride 10obinutuzumab 8Lenalidomide 8Immunotherapy, Adoptive 8Biopsy 8venetoclax 7polatuzumab vedotin 7pembrolizumab 7glofitamab 7zanubrutinib 6Dexamethasone 6tafasitamab 5ibrutinib 5etoposide phosphate 5acalabrutinib 5Leukapheresis 5tazemetostat 4loncastuximab tesirine 4Nivolumab 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Lymphoma, B-Cell × ibrutinib × 1 year × Clear all
NCT04662255 2026-05-15

BRUIN-MCL-321

Eli Lilly and Company

Phase 3 Active not recruiting
500 enrolled
Lymphoid

Hematologic Diseases, Lymphoma, Lymphoma, Non-Hodgkin, Lymphoma, B-Cell, Lymphoma, Mantle-Cell

NCT05254743 2026-04-20

BRUIN-CLL-314

Eli Lilly and Company

Phase 3 Recruiting
662 enrolled
LymphoidOther hematologic neoplasm

Hematologic Diseases, Leukemia, Lymphoid, Lymphoma, Non-Hodgkin, Leukemia, B-Cell, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell

NCT03478514 2026-04-09

Phase II Palbociclib +Ibrutinib in Mantle Cell Lymphoma

Alliance Foundation Trials, LLC.

Phase 2 Active not recruiting
39 enrolled
Lymphoid

Lymphoma, B-Cell, Lymphoma, Mantle-Cell

NCT03229200 2025-10-30

Extended Treatment Protocol for Subjects Continuing to Benefit From Ibrutinib.

Pharmacyclics Switzerland GmbH

Phase 4 Active not recruiting
297 enrolled
LymphoidOther hematologic neoplasm

Graft vs Host Disease, Lymphoma, Non-Hodgkin, Leukemia, B-Cell, Lymphoma, B-Cell

NCT03424122 2025-08-21

INCB050465 in Combination With Rituximab, Bendamustine and Rituximab, or Ibrutinib in Participants With Previously Treated B-Cell Lymphoma (CITADEL-112)

Incyte Corporation

Phase 1 Completed
50 enrolled
Lymphoid

Lymphoma, Follicular, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell

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