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Phase

Phase EARLY_PHASE1 1Phase 1/2 1

Status

Not yet recruiting 1Active not recruiting 1

Sponsor Class

NETWORK 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Lymphoid 2Other hematologic neoplasm 1

Conditions

Leukemia, Myeloid, Acute 108Leukemia, Lymphocytic, Chronic, B-Cell 30Myelodysplastic Syndromes 23Leukemia, Biphenotypic, Acute 11Recurrence 10Lymphoma, Mantle-Cell 9Leukemia 9Precursor Cell Lymphoblastic Leukemia-Lymphoma 8Leukemia, Myelomonocytic, Chronic 8Burkitt Lymphoma 8Waldenstrom Macroglobulinemia 7Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 7Lymphoma, B-Cell, Marginal Zone 7Lymphoma 7Hematologic Neoplasms 7Neoplasms 6Lymphoma, Large B-Cell, Diffuse 6Myeloproliferative Disorders 5Lymphoma, Non-Hodgkin 5Lymphoma, Follicular 4Leukemia, Myelogenous, Chronic, BCR-ABL Positive 4Multiple Myeloma 3Anemia, Refractory, with Excess of Blasts 3Sarcoma, Myeloid 2Myelodysplastic-Myeloproliferative Diseases 2Lymphoma, B-Cell 2Leukemia, Myeloid 2Immunoglobulin Light-chain Amyloidosis 2Blastic Plasmacytoid Dendritic Cell Neoplasm 2Blast Crisis 2

Interventions

Cyclophosphamide 23fludarabine 14Rituximab 14Specimen Handling 9Magnetic Resonance Spectroscopy 8Doxorubicin 7pirtobrutinib 6Vincristine 6Prednisone 6polatuzumab vedotin 5obinutuzumab 5Biopsy 5zanubrutinib 4glofitamab 4Nivolumab 4Etoposide 4Dexamethasone 4tazemetostat 3tafasitamab 3pembrolizumab 3ibrutinib 3fludarabine phosphate 3acalabrutinib 3Leukapheresis 3Bendamustine Hydrochloride 3venetoclax 2pomalidomide 2loncastuximab tesirine 2etoposide phosphate 2cemiplimab 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Lymphoma, B-Cell × venetoclax × 90 days × Clear all
NCT04161248 2026-05-12

Phase I Master Protocol of Novel Combination Therapy for Patients With Relapsed or Refractory Aggressive B-Cell Lymphoma

Canadian Cancer Trials Group

Phase EARLY_PHASE1 Active not recruiting
40 enrolled
Lymphoid

Lymphoma, B-Cell

NCT07520006 2026-04-13

Study of NX-5948 in Combination With Other Agents in Adults With B-cell Malignancies

Nurix Therapeutics, Inc.

Phase 1/2 Not yet recruiting
150 enrolled
LymphoidOther hematologic neoplasm

Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell

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