Announcements Trials
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Phase

Phase 1 3

Status

Completed 2Terminated 1

Sponsor Class

OTHER 17NIH 3INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Lymphoid 3Other hematologic neoplasm 2

Conditions

Melanoma 30Leukemia, Lymphocytic, Chronic, B-Cell 28Leukemia 26Lymphoma 19Leukemia, Myeloid, Acute 18Myelodysplastic Syndromes 17Precursor Cell Lymphoblastic Leukemia-Lymphoma 16Multiple Myeloma 15Neoplasm Metastasis 13Lymphoma, Follicular 12Skin Neoplasms 11Lymphoma, Mantle-Cell 10Leukemia, Myelomonocytic, Chronic 10Leukemia, Myeloid, Accelerated Phase 10Hodgkin Disease 10Congenital Abnormalities 10Lymphoma, Non-Hodgkin 9Lymphoma, B-Cell, Marginal Zone 9Leukemia, Myeloid, Chronic-Phase 9Myeloproliferative Disorders 8Blast Crisis 8Anemia, Refractory, with Excess of Blasts 8Neoplasms, Plasma Cell 7Lymphoma, Large B-Cell, Diffuse 7Kidney Neoplasms 7Burkitt Lymphoma 7Primary Myelofibrosis 6Neoplasms 6Myelodysplastic-Myeloproliferative Diseases 6Lymphoma, Large-Cell, Immunoblastic 6

Interventions

Cyclophosphamide 11Rituximab 6Prednisone 6fludarabine 5Vincristine 5Doxorubicin 5Etoposide 4fludarabine phosphate 3Bortezomib 3Specimen Handling 2Nivolumab 2Magnetic Resonance Spectroscopy 2Magnetic Resonance Imaging 2MLN 8237 2Electrocardiography 2Echocardiography 2Diphenhydramine 2CT-P10 2Automobiles 2Acetaminophen 2venetoclax 1varlilumab 1tositumomab I-131 1tazemetostat 1saponin QA-21V1 1romidepsin 1pomalidomide 1obinutuzumab 1molibresib 1magrolimab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
NIH × Lymphoma, B-Cell × fludarabine phosphate × Clear all
NCT03448393 2025-06-04

CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
54 enrolled 24 charts
LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Lymphoma, Lymphoma, Non-Hodgkin, Philadelphia Chromosome, Leukemia, B-Cell, Lymphoma, B-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02659943 2023-04-19

T Cells Expressing a Fully-human AntiCD19 Chimeric Antigen Receptor for Treating B-cell Malignancies

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
27 enrolled 25 charts
Lymphoid

Lymphoma, Non-Hodgkin, Lymphoma, B-Cell

NCT04160195 2022-02-15

T Cells Expressing Fully-human Anti-CD19 and Anti-CD20 Chimeric Antigen Receptors for Treating B-cell Malignancies and Hodgkin Lymphoma

National Institutes of Health Clinical Center (CC)

Phase 1 Terminated
2 enrolled 14 charts
LymphoidOther hematologic neoplasm

Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell

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