Announcements Trials
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Phase

Phase 1/2 3Phase 2 1

Status

Withdrawn 2Recruiting 1Completed 1

Sponsor Class

OTHER 2INDUSTRY 2

Study Type

Interventional 4

Sponsor

Cancer Type

Lymphoid 4Thoracic 1Plasma cell 1

Conditions

Carcinoma, Non-Small-Cell Lung 22Lung Neoplasms 9Lymphoma, Large-Cell, Anaplastic 4Carcinoma 4Carcinoma, Squamous Cell 2Carcinoma, Large Cell 2Brain Neoplasms 2Adenocarcinoma 2ALK-positive Advanced NSCLC 2Sexual Dysfunction, Physiological 1Neuroma, Acoustic 1Neurofibromatosis 2 1Neoplasms 1Neoplasm Metastasis 1NSCLC 1Meningioma 1Granuloma, Plasma Cell 1Gastrointestinal Neoplasms 1Eunuchism 1Erectile Dysfunction 1Ependymoma 1Disease Progression 1Carcinoma, Pancreatic Ductal 1Breast Neoplasms 1ALK-positive NSCLC 1ALK+ Advanced NSCLC 1

Interventions

Cyclophosphamide 65Peripheral Blood Stem Cell Transplantation 37fludarabine phosphate 36Doxorubicin 31Etoposide 30Vincristine 29Whole-Body Irradiation 28Rituximab 26Prednisone 26Brentuximab Vedotin 26Mycophenolic Acid 25Filgrastim 22Cyclosporine 22Methotrexate 20Busulfan 19Cytarabine 18Radiotherapy 17Antilymphocyte Serum 16Tacrolimus 15Melphalan 15Carboplatin 14Ifosfamide 13Bortezomib 13Methylprednisolone 12Gemcitabine 11Flow Cytometry 10Lenalidomide 9Dexamethasone 9romidepsin 8Vorinostat 8

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Lymphoma, Large-Cell, Anaplastic × brigatinib × Clear all
NCT04925609 2025-12-05

Briga-PED

Princess Maxima Center for Pediatric Oncology

Phase 1/2 Recruiting
65 enrolled
LymphoidPlasma cell

Granuloma, Plasma Cell, Lymphoma, Large-Cell, Anaplastic

NCT01449461 2021-08-17

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-Tumor Activity of the Oral Anaplastic Lymphoma Kinase (ALK)/Epidermal Growth Factor Receptor (EGFR) Inhibitor Brigatinib (AP26113)

Takeda

Phase 1/2 Completed
137 enrolled 38 charts
LymphoidThoracic

Carcinoma, Non-Small-Cell Lung, Lymphoma, Large-Cell, Anaplastic

NCT03719898 2021-01-05

Brigatinib in Relapsed or Refractory ALK-Positive Anaplastic Large Cell Lymphoma

Fox Chase Cancer Center

Phase 2 Withdrawn
Lymphoid

Lymphoma, Large-Cell, Anaplastic

NCT04260009 2020-03-05

Pharmacokinetics, Safety, and Efficacy of Brigatinib Monotherapy in Pediatric and Young Adult Participants With ALK+ Anaplastic Large Cell Lymphoma, Inflammatory Myofibroblastic Tumors or Other Solid Tumors

Takeda

Phase 1/2 Withdrawn
Lymphoid

Lymphoma, Large-Cell, Anaplastic

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