Announcements Trials
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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Lymphoid 1

Conditions

Sarcoma 5Rhabdoid Tumor 4Lymphoma, Large B-Cell, Diffuse 4Lymphoma, Follicular 4Sarcoma, Synovial 3Lymphoma, Non-Hodgkin 3Lymphoma, B-Cell 3Wilms Tumor 2Sarcoma, Ewing 2Rhabdomyosarcoma 2Recurrence 2Osteosarcoma 2Neuroectodermal Tumors, Primitive, Peripheral 2Neuroblastoma 2Mesothelioma 2Medulloblastoma 2Histiocytosis, Langerhans-Cell 2Hepatoblastoma 2Glioma 2Ependymoma 2Central Nervous System Neoplasms 2Xanthogranuloma, Juvenile 1Prostatic Neoplasms 1Ovarian Neoplasms 1Neurofibrosarcoma 1Nerve Sheath Neoplasms 1Lymphoma, Mantle-Cell 1Lymphoma, B-Cell, Marginal Zone 1Inhibition, Psychological 1Hodgkin Disease 1

Interventions

Rituximab 93Cyclophosphamide 72fludarabine phosphate 53Whole-Body Irradiation 43Mycophenolic Acid 40Peripheral Blood Stem Cell Transplantation 39Bortezomib 30Tacrolimus 29Etoposide 29Cyclosporine 28Melphalan 26Filgrastim 26Busulfan 26Methotrexate 24Lenalidomide 23Cytarabine 23ibrutinib 20Vincristine 20Granulocyte Colony-Stimulating Factor 20Antilymphocyte Serum 20Doxorubicin 18Bendamustine Hydrochloride 18Dexamethasone 16Sirolimus 14fludarabine 13Carmustine 13Cord Blood Stem Cell Transplantation 12Calcium Dobesilate 12Radiotherapy 11Prednisone 11

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Has results × Lymphoma, Mantle-Cell × tazemetostat × Clear all
NCT03028103 2023-06-26

Open-Label, Multicenter, Two-Part, Phase 1 Study to Characterize Effects of a Moderate CYP3A Inhibitor on PK of Tazemetostat, Effects of Tazemetostat on PK of CYP2C8 and CYP2C19 Substrates, and Effect of Increased Gastric pH on PK of Tazemetostat in B-cell Lymphoma or Advanced Solid Tumor Patients

Ipsen

Phase 1 Completed
32 enrolled 30 charts
Lymphoid

Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell

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