Announcements Trials
Browse Landscape

Phase

Phase 2 5Phase EARLY_PHASE1 1

Status

Recruiting 2Completed 2Active not recruiting 2Available 1Approved for marketing 1

Sponsor Class

INDUSTRY 5OTHER 3

Study Type

Interventional 6Expanded_access 2

Sponsor

Cancer Type

Lymphoid 8Other hematologic neoplasm 1

Conditions

Lymphoma, Mantle-Cell 8Recurrence 6Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Lymphoma, B-Cell 2Burkitt Lymphoma 2Waldenstrom Macroglobulinemia 1Lymphoma 1Leukemia, Lymphocytic, Chronic, B-Cell 1Leukemia, Hairy Cell 1Hematologic Neoplasms 1

Interventions

Rituximab 226Cyclophosphamide 202fludarabine phosphate 108Peripheral Blood Stem Cell Transplantation 103Filgrastim 87Etoposide 76Cytarabine 70ibrutinib 68Mycophenolic Acid 67Bortezomib 66Whole-Body Irradiation 63Cyclosporine 63Melphalan 59Lenalidomide 59Bendamustine Hydrochloride 58Vincristine 53Radiotherapy 53fludarabine 52Tacrolimus 50Doxorubicin 48Busulfan 48Methotrexate 47Antilymphocyte Serum 42Prednisone 41Carmustine 40Dexamethasone 38Granulocyte Colony-Stimulating Factor 33venetoclax 32acalabrutinib 31zanubrutinib 26

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

8 trials
RecentStart dateEnrollment
Lymphoma, Mantle-Cell × brexucabtagene autoleucel × Clear all
NCT05495464 2026-05-20

A Pilot "Window-3" Study of Acalabrutinib Plus Rituximab Followed by Brexucabtagene Autoleucel Therapy in Patients With Previously Untreated High-risk Mantle Cell Lymphoma

M.D. Anderson Cancer Center

Phase EARLY_PHASE1 Active not recruiting
22 enrolled
Lymphoid

Lymphoma, Lymphoma, Mantle-Cell

NCT05776134 2026-04-08

Expanded Access Study for the Treatment of Patients With Commercially Out-of-Specification Brexucabtagene Autoleucel

Gilead Sciences

Available
LymphoidOther hematologic neoplasm

Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT06553872 2026-03-31

Phase 2 Open Label Randomized Study of Pirtobrutinib and Brexucabtagene Autoleucel in R/R MCL

H. Lee Moffitt Cancer Center and Research Institute

Phase 2 Recruiting
60 enrolled
Lymphoid

Lymphoma, Mantle-Cell

NCT02601313 2026-03-18

ZUMA-2

Gilead Sciences

Phase 2 Completed
105 enrolled 33 charts 1 FDA
Lymphoid

Lymphoma, Mantle-Cell

NCT06253663 2025-12-16

JKART-1

Gilead Sciences

Phase 2 Active not recruiting
25 enrolled
Lymphoid

Recurrence, Lymphoma, Mantle-Cell

NCT04880434 2025-11-17

ZUMA-2

Gilead Sciences

Phase 2 Completed
95 enrolled
Lymphoid

Lymphoma, Mantle-Cell

NCT06482684 2024-07-01

CARMAN

Ludwig-Maximilians - University of Munich

Phase 2 Recruiting
150 enrolled
Lymphoid

Lymphoma, Mantle-Cell

NCT04162756 2021-10-14

ZUMA-18

Gilead Sciences

Approved for marketing
Lymphoid

Recurrence, Lymphoma, Mantle-Cell

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