Announcements Trials
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Phase

Phase 1 2

Status

Completed 2

Sponsor Class

NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

Lymphoid 2Dermatologic 2Other hematologic neoplasm 1

Conditions

Sezary Syndrome 2Mycosis Fungoides 2Melanoma 2Lymphoma, T-Cell, Cutaneous 2Carcinoma, Renal Cell 2Squamous Cell Carcinoma of Head and Neck 1Skin Neoplasms 1Sarcoma 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Neuroblastoma 1Lymphoma, T-Cell, Peripheral 1Lymphoma, T-Cell 1Lymphoma, Large-Cell, Anaplastic 1Lymphoma 1Leukemia-Lymphoma, Adult T-Cell 1Leukemia, Prolymphocytic, T-Cell 1Leukemia 1Carcinoma, Non-Small-Cell Lung 1Carcinoma 1Bronchiolitis Obliterans Syndrome 1Brain Neoplasms 1

Interventions

romidepsin 5fludarabine phosphate 5Cyclosporine 5Biopsy 5tanespimycin 4Gemcitabine 4belinostat 3aldesleukin 3Vorinostat 3Polymerase Chain Reaction 3Peripheral Blood Stem Cell Transplantation 3Methylprednisolone 3Magnetic Resonance Spectroscopy 3Lenalidomide 3Irinotecan 3Flow Cytometry 3Busulfan 3Bortezomib 3B3(Fv)-PE38KDEL recombinant immunotoxin 3Antilymphocyte Serum 3nelarabine 2laromustine 2fludarabine 2entinostat 2alvocidib 2Specimen Handling 2Psychiatric Rehabilitation 2Pharmacogenomic Testing 2O(6)-benzylguanine 2Mycophenolic Acid 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
NIH × Lymphoma, T-Cell, Cutaneous × Interleukin-15 × Clear all
NCT03905135 2022-09-13

Interleukin-15 (IL-5) in Combination With Avelumab (Bavencio) in Relapsed/Refractory Mature T-cell Malignancies

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
8 enrolled 18 charts
DermatologicLymphoid

Mycosis Fungoides, Sezary Syndrome, Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic

NCT02689453 2022-04-29

Subcutaneous Recombinant Human IL-15 (s.c. rhIL-15) and Alemtuzumab for People With Refractory or Relapsed Chronic and Acute Adult T-cell Leukemia (ATL)

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
11 enrolled 16 charts
DermatologicLymphoidOther hematologic neoplasm

Leukemia-Lymphoma, Adult T-Cell, Leukemia, Prolymphocytic, T-Cell, Lymphoma, T-Cell, Cutaneous, Lymphoma, T-Cell, Peripheral

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