Announcements Trials
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Phase

Phase 2 2Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1Lymphoid 1

Conditions

Leukemia, Myeloid, Acute 95Myelodysplastic Syndromes 26Recurrence 25Lymphoma, Non-Hodgkin 24Neoplasms 21Leukemia, Lymphocytic, Chronic, B-Cell 19Lymphoma, Large B-Cell, Diffuse 15Leukemia 12Lymphoma, Follicular 10Multiple Myeloma 9Hematologic Neoplasms 9Lymphoma, B-Cell, Marginal Zone 8Burkitt Lymphoma 7Lymphoma, Mantle-Cell 6Lymphoma, B-Cell 6Lymphoma 6Leukemia, Myelomonocytic, Chronic 6Leukemia, Myeloid 6Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Neoplasm Metastasis 4Myeloproliferative Disorders 4Leukemia, Biphenotypic, Acute 4Small Cell Lung Carcinoma 3Prostatic Neoplasms 3GATA2 Deficiency 3Carcinoma, Non-Small-Cell Lung 3Breast Neoplasms 3Primary Myelofibrosis 2Immunoglobulin Light-chain Amyloidosis 2Colorectal Neoplasms 2

Interventions

romidepsin 8Vincristine 6Cyclophosphamide 6Specimen Handling 5Rituximab 5Biopsy 5fludarabine 4Prednisone 4Methotrexate 4Magnetic Resonance Spectroscopy 4Lactones 4Doxorubicin 4Depsipeptides 4ruxolitinib 3duvelisib 3belinostat 3Nivolumab 3Etoposide 3Dexamethasone 3Cytarabine 3Calcium Dobesilate 3Bortezomib 3Azacitidine 3tazemetostat 2sodium-iodide symporter 2pegaspargase 2merphos 2liposomal doxorubicin 2cemiplimab 2X-Rays 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1 × Lymphoma, T-Cell × venetoclax × Clear all
NCT05665530 2026-01-26

A Study of PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With R/R Hematologic Malignancies

Prelude Therapeutics

Phase 1 Completed
86 enrolled
LymphoidMyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Recurrence, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, T-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Hematologic Neoplasms, Lymphoma, Mantle-Cell

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