Clinical Trials

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Margins of Excision, Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms

NCT07517198 2026-04-08

Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors

Phase 1 Recruiting

40 enrolled

Margins of Excision, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Liver Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT06020573 2026-04-07

Evaluation of Safety and Performance of Intraoperative Detection of Light Signals During Electrosurgical Breast Cancer Resection

24 enrolled

Phase NA Not yet recruiting

Margins of Excision, Breast Neoplasms

NCT07352930 2026-03-24

A Novel Intraoperative Fluorescence-guided System for Evaluating Margins During Breast-conserving Surgery for Breast Cancer

172 enrolled

Margins of Excision

NCT07132190 2026-03-19

Stereotactic Radiation for Growing/Changing Brain Metastases With Same-Day Radiation Planning and Treatment With Margin Reduction

Phase 2 Recruiting

60 enrolled

CNS

Margins of Excision, Brain Neoplasms, Fasting

NCT04073745 2026-02-04

Single Fraction Stereotactic Body Radiation Therapy After Surgery in Treating Patients With Non-small Cell Lung Cancer

Phase 1 Active not recruiting

50 enrolled

Thoracic

Margins of Excision, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT07285564 2025-12-16

TEP Margins

10 enrolled

Phase NA Active not recruiting

Margins of Excision, Head and Neck Neoplasms

NCT05935995 2025-11-28

HISTOBLOC

42 enrolled

DermatologicHead & Neck

Margins of Excision, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell

NCT07242053 2025-11-21

Margin Intraoperative CT Feedback Feedback Study

Phase NA Active not recruiting

80 enrolled

Thoracic

Margins of Excision, Disease, Lung Neoplasms

NCT07141121 2025-10-07

IMARHGIN

78 enrolled

Margins of Excision, Prostatic Neoplasms

NCT05782686 2025-09-15

Impact of Systematic Shaving on Margins

234 enrolled

Phase NA Not yet recruiting

Margins of Excision, Breast Neoplasms

NCT07029646 2025-06-19

Comparative Research on the Accuracy of Margin Interpretation in Breast-Conserving Surgery for Breast Cancer: Cell Microscopic Imaging and Standard Frozen Pathology

167 enrolled

Margins of Excision, Breast Neoplasms

NCT04738786 2025-05-18

Clinical Study Evaluating the Proper Surgical Safety Margin for Early Stage Oral Tongue Cancers

Phase NA Terminated

125 enrolled

Margins of Excision, Carcinoma, Squamous Cell, Tongue Neoplasms

NCT05825768 2025-01-30

PRIMAR

Phase NA Terminated

227 enrolled

Margins of Excision, Breast Neoplasms

NCT06778603 2025-01-16

ROLN-B7-H3

Phase 1/2 Recruiting

32 enrolled

Sarcoma

Margins of Excision, Osteosarcoma

NCT06398470 2025-01-10

Study to Evaluate a New Method to Detect Residual Tumours During Surgery for Prostate Cancer Using Confocal Microscopy

Phase 1/2 Completed

21 enrolled

Phase NA Not yet recruiting

Margins of Excision, Prostatic Neoplasms

NCT06709170 2024-11-29

Safety & Efficacy of a Novel Asymmetrical Linear Stapler (NALS) for Securing Distal Resection Margin in Laparoscopic Rectal Cancer Surgery: Pilot Study

60 enrolled

Margins of Excision, Colonic Neoplasms, Rectal Neoplasms

NCT06342297 2024-04-02

Dermatoscopy Guided Resection for Skin Cancer

400 enrolled

Dermatologic

Margins of Excision, Carcinoma, Basal Cell

NCT06289803 2024-03-04

The Application of Probe Confocal Laser Endomicroscopy in Pancreatic Tumor Surgery

200 enrolled

Margins of Excision, Disease, Pancreatic Neoplasms

NCT02027818 2023-12-15

Study of the ICG Distribution in the Margins of Breast Cancer After Tumorectomy

20 enrolled

Margins of Excision, Breast Neoplasms

NCT02649647 2023-12-06

PERN

240 enrolled

Margins of Excision, Rectal Neoplasms

NCT05859581 2023-05-16

The Value of MRI in Assessing the Status of Retroperitoneal Resection Margin in Colon Cancer

29 enrolled

Margins of Excision, Colonic Neoplasms

NCT05456373 2023-03-22

Intraoperative Use of ClearEdge Device in Breast Conserving Surgery

288 enrolled

Margins of Excision, Breast Neoplasms

NCT04918381 2023-01-11

CellFX Treat & Resect Low-Risk BCC Feasibility Study

30 enrolled 6 charts

Dermatologic

Margins of Excision, Carcinoma, Basal Cell

NCT04389086 2022-09-06

PelvEx II

Phase 3 Recruiting

364 enrolled

Margins of Excision, Rectal Neoplasms

NCT04136522 2022-07-20

Usefulness of the Artery First Approach in Pancreatic Cancer Surgery

268 enrolled

Phase NA Active not recruiting

Pancreatic cancer, adult, Margins of Excision, Recurrence

NCT05459415 2022-07-15

Reducing Excision Margins After Neoadjuvant Chemoimmunotherapy for HPV Negative Resectable Locally Advanced HNSCC

54 enrolled

Margins of Excision, Squamous Cell Carcinoma of Head and Neck

NCT04059861 2021-12-27

Ultrasound in Tongue Cancer- a Help to Decide Depth of Invasion and to Improve the Surgical Margin

42 enrolled

Margins of Excision, Tongue Neoplasms

NCT03975179 2021-10-21

OFF-MAP

1,292 enrolled

Margins of Excision, Breast Neoplasms

NCT05044624 2021-09-16

Retroperıtoneal Soft-Tıssue Sarcomas

18 enrolled

Sarcoma

Margins of Excision, Sarcoma

NCT04683120 2021-06-30

Real-time Diagnosis and Visualization of Tumor Margins in Excised Breast Specimens Using Zenith FLIM Diagnostics

Phase NA Suspended

100 enrolled

Margins of Excision, Breast Neoplasms, Neoplasms

NCT03417622 2021-02-25

Wide Margin vs. Narrow Margin in Postneoadjuvant Lumpectomy

Phase 3 Recruiting

370 enrolled

Margins of Excision, Breast Neoplasms

NCT04418089 2020-06-05

Simvastatin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response and Tumor-Free Margin in Locally Advanced Breast Cancer

60 enrolled

Margins of Excision, Breast Neoplasms

NCT04344847 2020-04-14

Incidental Finding of Gastrointestinal Stromal Tumors (GISTs) During Laparoscopic Sleeve Gastrectomy, How to Deal? How Much Safety Margin

338 enrolled

GastrointestinalSarcoma

Margins of Excision, Gastrointestinal Stromal Tumors

NCT02159703 2019-11-21

A Single-arm Phase II Study of Post-Transoral Robotic Surgery (TORS) Alone to the Primary Tumor Site and Selective Neck Dissection (SND) Followed by Adjuvant Radiation Therapy (+/- Chemotherapy) to the Regional Nodes for Advanced Stage, Human Papilloma Virus (HPV) Positive, Oropharyngeal Cancer

60 enrolled 9 charts

Margins of Excision, Oropharyngeal Neoplasms

NCT04129606 2019-10-17

TURBT-BP

300 enrolled

Margins of Excision, Urinary Bladder Neoplasms, Neoplasm Seeding, Recurrence, Wounds and Injuries

NCT02189226 2019-04-01

Usefulness of Probe-based Confocal Laser Endo-microscopy in Delineation of Margin of Early Gastric Cancer for Endoscopic Submucosal Dissection

101 enrolled

Margins of Excision, Stomach Neoplasms

NCT02035735 2018-12-11

Interest of Narrow Band Imaging in Detection of Upper Aerodigestive Cancers

93 enrolled

Margins of Excision, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Laryngeal Diseases

NCT03638492 2018-08-20

Trial of Surgical Excision Margins in Thick Primary Melanoma - 2

DermatologicGenitourinaryGynecologicLymphoidOther hematologic neoplasmThoracic

936 enrolled

Dermatologic

Margins of Excision, Melanoma

NCT01460134 2018-01-31

A Study of CDX-1127 (Varlilumab) in Patients With Select Solid Tumor Types or Hematologic Cancers

Phase 1 Completed

90 enrolled

Margins of Excision, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma, Ovarian Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell

NCT02313688 2017-12-11

Length of the Proximal Resection Margin for Siewert-II/Siewert-III Tumors

320 enrolled

Margins of Excision, Recurrence, Stomach Neoplasms

NCT01784978 2017-10-02

SUNRISES

Phase 2 Terminated

41 enrolled

Margins of Excision, Carcinoma, Renal Cell, Neoplasm Metastasis, Neoplasms

NCT00719264 2017-03-20

Safety and Efficacy of Bevacizumab Plus RAD001 Versus Interferon Alfa-2a and Bevacizumab for the First-line Treatment in Adult Patients With Kidney Cancer

365 enrolled 14 charts

Margins of Excision, Adenocarcinoma, Carcinoma, Carcinoma, Renal Cell

NCT02900950 2016-09-15

MPM

68 enrolled

Margins of Excision, Neoplasms, Pancreatic Neoplasms, Neoplasm, Residual

NCT02260349 2016-03-10

Interest of Indocyanine Green in Neoplastic Prostatic Tissue

Phase 3 Withdrawn

Margins of Excision, Prostatic Neoplasms

NCT02460861 2015-06-03

iPROLOGX

279 enrolled

Margins of Excision, Prostatic Neoplasms

NCT01039298 2014-09-10

Efficacy of Optically-guided Surgery in the Management of Early-staged Oral Cancer - COOLS TRIAL

Phase 3 Unknown

200 enrolled