Announcements Trials
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Phase

Phase 4 1Phase 3 1Phase 2 1Phase 1 1

Status

Withdrawn 1Recruiting 1Completed 1Active not recruiting 1

Sponsor Class

OTHER 3NETWORK 1

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 4

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 49Burkitt Lymphoma 27Leukemia, Biphenotypic, Acute 15Leukemia, Myeloid, Acute 13Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 10Leukemia 10Myelodysplastic Syndromes 9Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 7Lymphoma 6Leukemia, Myeloid, Accelerated Phase 6Blast Crisis 6Lymphoma, Non-Hodgkin 5Lymphoma, Mantle-Cell 5Lymphoma, Large B-Cell, Diffuse 5Graft vs Host Disease 5Osteosarcoma 4Medulloblastoma 4Down Syndrome 4Urinary Bladder Neoplasms 3Recurrence 3Primary Myelofibrosis 3Neoplasm Metastasis 3Myeloproliferative Disorders 3Leukemia, Myelomonocytic, Juvenile 3Hematologic Neoplasms 3Head and Neck Neoplasms 3Blastic Plasmacytoid Dendritic Cell Neoplasm 3Thrombocythemia, Essential 2Rhabdoid Tumor 2Polycythemia Vera 2

Interventions

Cyclophosphamide 14Temozolomide 11Vincristine 9Magnetic Resonance Spectroscopy 9Cisplatin 9Etoposide 8Specimen Handling 7Radiotherapy 7X-Rays 6Phantoms, Imaging 6Nuclear Medicine Department, Hospital 5Lomustine 5Carboplatin 5Methotrexate 4Irinotecan 4Biopsy 4etoposide phosphate 3Thiotepa 3Radiation 3Platinum 3Nivolumab 3Filgrastim 3Celecoxib 3Bevacizumab 3Automobiles 31,2-diaminocyclohexaneplatinum II citrate 3ulixertinib 2tipifarnib 2tazemetostat 2selpercatinib 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Medulloblastoma × Methotrexate × 1 year × Clear all
NCT02875314 2026-06-03

HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors

Nationwide Children's Hospital

Phase 4 Active not recruiting
250 enrolled
CNS

Medulloblastoma

NCT05535166 2026-02-12

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

St. Jude Children's Research Hospital

Phase 2 Recruiting
130 enrolled
CNS

Brain Neoplasms, Medulloblastoma

NCT00336024 2026-01-23

Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma

Children's Oncology Group

Phase 3 Completed
91 enrolled 24 charts
CNS

Medulloblastoma

NCT06466798 2026-01-08

Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies

The University of Texas Health Science Center, Houston

Phase 1 Withdrawn
CNS

Ependymoma, Medulloblastoma, Central Nervous System Neoplasms

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