Announcements Trials
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Phase

Phase 1 1

Status

Terminated 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Other hematologic neoplasm 1Lymphoid 1Endocrine 1CNS 1

Conditions

Multiple Myeloma 43Precursor Cell Lymphoblastic Leukemia-Lymphoma 14Recurrence 7Lymphoma, Non-Hodgkin 6Burkitt Lymphoma 6Neoplasms, Plasma Cell 5Nausea 5Leukemia 5Vomiting 4Prostatic Neoplasms 4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 4Neoplasms 4Lymphoma 4Neoplasm Metastasis 3Lymphoma, Large B-Cell, Diffuse 3Hematologic Neoplasms 3Amyloidosis 3Smoldering Multiple Myeloma 2Oligodendroglioma 2Lung Neoplasms 2Leukemia, Myeloid, Acute 2Leukemia, Biphenotypic, Acute 2Immunoglobulin Light-chain Amyloidosis 2Carcinoma, Non-Small-Cell Lung 2Breast Neoplasms 2Astrocytoma 2Waldenstrom Macroglobulinemia 1Uveal Melanoma 1Squamous Cell Carcinoma of Head and Neck 1Spinal Cord Neoplasms 1

Interventions

Filgrastim 4Cyclophosphamide 4Vincristine 3Topotecan 3Melphalan 3Lomustine 3Granulocyte Colony-Stimulating Factor 3Cisplatin 3etoposide phosphate 2Thiotepa 2Temozolomide 2Radiotherapy 2Mesna 2Ifosfamide 2Etoposide 2Carboplatin 2Busulfan 2sonidegib 1sodium thiosulfate 1silmitasertib 1sargramostim 1ribociclib 1poly ICLC 1palbociclib 1omburtamab I-131 1gadobutrol 1gadobenic acid 1bempegaldesleukin 1Yoga 1Vaccines 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Terminated × Medulloblastoma × Calcium Dobesilate × Clear all
NCT01088763 2014-11-05

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

National Cancer Institute (NCI)

Phase 1 Terminated
129 enrolled
CNSEndocrineLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Adenoma, Basophil, Adenoma, Chromophobe, Adenoma, Acidophil, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Oligodendroglioma, Pituitary Neoplasms, Recurrence, Spinal Cord Neoplasms, Prolactinoma, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Rhabdoid Tumor, Optic Nerve Glioma, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

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