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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Glioblastoma 6Brain Neoplasms 4Oligodendroglioma 3Lymphoma, Follicular 3Gliosarcoma 3Carcinoma, Non-Small-Cell Lung 3Astrocytoma 3Prostatic Neoplasms 2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Optic Nerve Glioma 2Lymphoma, T-Cell, Cutaneous 2Lymphoma, Non-Hodgkin 2Lymphoma, Mantle-Cell 2Lymphoma, Large-Cell, Immunoblastic 2Lymphoma, Large B-Cell, Diffuse 2Lymphoma, B-Cell, Marginal Zone 2Leukemia, Lymphocytic, Chronic, B-Cell 2Immunoblastic Lymphadenopathy 2Hodgkin Disease 2Central Nervous System Neoplasms 2Burkitt Lymphoma 2Waldenstrom Macroglobulinemia 1Unspecified Adult Solid Tumor, Protocol Specific 1Triple Negative Breast Neoplasms 1Thrombocythemia, Essential 1Sezary Syndrome 1Renal Insufficiency 1Recurrence 1Primary Myelofibrosis 1

Interventions

Filgrastim 19Temozolomide 18Cyclophosphamide 16Carboplatin 15Etoposide 12Vincristine 11Peripheral Blood Stem Cell Transplantation 10Cisplatin 10Radiotherapy 9Irinotecan 9Thiotepa 8Granulocyte Colony-Stimulating Factor 7sonidegib 5Methotrexate 5sargramostim 4Vorinostat 4Magnetic Resonance Spectroscopy 4Lomustine 4Chemotherapy, Adjuvant 4Carmustine 4etoposide phosphate 3Topotecan 3Radiation 3Platinum 3Paclitaxel 3Oxaliplatin 3O(6)-benzylguanine 3Melphalan 3HhAntag691 3Granulocyte-Macrophage Colony-Stimulating Factor 3

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Completed × Medulloblastoma × Cilengitide × Clear all
NCT00063973 2013-09-30

Cilengitide in Treating Children With Refractory Primary Brain Tumors

National Cancer Institute (NCI)

Phase 1 Completed
24 enrolled
CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Choroid Plexus Neoplasms, Optic Nerve Glioma

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