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Phase

Phase 2 11Phase 3 4Phase EARLY_PHASE1 2Phase NA 1Phase 4 1Phase 2/3 1Phase 1/2 1Phase 1 1

Status

Terminated 1Recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2

Conditions

Head and Neck Neoplasms 4Stomach Neoplasms 2Squamous Cell Carcinoma of Head and Neck 2Ovarian Neoplasms 2Medulloblastoma 2Fallopian Tube Neoplasms 2Tonsillar Neoplasms 1Sarcoma 1Rhabdomyosarcoma 1Rhabdoid Tumor 1Rectal Neoplasms 1Pyloric Stenosis, Hypertrophic 1Prostatic Neoplasms 1Pinealoma 1Pharyngeal Neoplasms 1Pelvic Neoplasms 1Pancreatic Adenocarcinoma 1Ototoxicity 1Neuroectodermal Tumors, Primitive 1Neuroblastoma 1Neoplasms, Germ Cell and Embryonal 1Muscle Invasive Bladder Urothelial Carcinoma 1Mesothelioma, Malignant 1Lymphoma, B-Cell 1Liposarcoma 1Hepatoblastoma 1Esophageal Squamous Cell Carcinoma 1EGFR Positive Non-small Cell Lung Cancer 1Desmoplastic Small Round Cell Tumor 1Colonic Neoplasms 1

Interventions

etoposide phosphate 2Vincristine 2Methotrexate 2Mesna 2Etoposide 2Cyclophosphamide 2Cisplatin 2ribociclib 1palbociclib 1fimepinostat 1abemaciclib 1Thiotepa 1Therapeutics 1Temozolomide 1Tamoxifen 1Lomustine 1Leucovorin 1Isotretinoin 1Hydrocortisone 1Granulocyte Colony-Stimulating Factor 1Filgrastim 1Donepezil 1Celecoxib 1Carboplatin 1CUDC-907 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase EARLY_PHASE1 × Medulloblastoma × Cisplatin × Clear all
NCT06942039 2026-02-27

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

C17 Council

Phase EARLY_PHASE1 Recruiting
15 enrolled
CNS

Medulloblastoma, Neuroblastoma, Pinealoma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor, Pyloric Stenosis, Hypertrophic

NCT02212574 2021-11-05

Study Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive Medulloblastoma

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase EARLY_PHASE1 Terminated
6 enrolled 6 charts
CNS

Medulloblastoma

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