Announcements Trials
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Phase

Phase 1 2

Status

Completed 2Recruiting 1Active not recruiting 1

Sponsor Class

NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Sarcoma 1Other hematologic neoplasm 1Lymphoid 1

Conditions

Neuroblastoma 24Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Lung Neoplasms 3Leukemia, Myelomonocytic, Juvenile 3Head and Neck Neoplasms 3Uterine Cervical Neoplasms 2Squamous Cell Carcinoma of Head and Neck 2Small Cell Lung Carcinoma 2Recurrence 2Neoplasms 2Myelodysplastic Syndromes 2Mycosis Fungoides 2Medulloblastoma 2Lymphoma, Large B-Cell, Diffuse 2Leukemia, Myeloid, Acute 2Kidney Neoplasms 2HIV Infections 2Ganglioneuroblastoma 2Central Nervous System Neoplasms 2Carcinoma, Renal Cell 2Carcinoma, Non-Small-Cell Lung 2Burkitt Lymphoma 2Brain Neoplasms 2Acquired Immunodeficiency Syndrome 2AIDS-Related Complex 2Waldenstrom Macroglobulinemia 1Uterine Cervical Dysplasia 1Uterine Cervical Diseases 1Tumor Virus Infections 1Thrombocytopenia 1

Interventions

Filgrastim 19Temozolomide 18Cyclophosphamide 16Carboplatin 15Etoposide 12Vincristine 11Peripheral Blood Stem Cell Transplantation 10Cisplatin 10Radiotherapy 9Irinotecan 9Thiotepa 8Granulocyte Colony-Stimulating Factor 7sonidegib 5Methotrexate 5sargramostim 4Vorinostat 4Magnetic Resonance Spectroscopy 4Lomustine 4Chemotherapy, Adjuvant 4Carmustine 4etoposide phosphate 3Topotecan 3Radiation 3Platinum 3Paclitaxel 3Oxaliplatin 3O(6)-benzylguanine 3Melphalan 3HhAntag691 3Granulocyte-Macrophage Colony-Stimulating Factor 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Completed × Medulloblastoma × Isotretinoin × Clear all
NCT00867178 2022-01-13

Vorinostat Combined With Isotretinoin and Chemotherapy in Treating Younger Patients With Embryonal Tumors of the Central Nervous System

National Cancer Institute (NCI)

Phase 1 Completed
33 enrolled
CNS

Medulloblastoma, Pinealoma

NCT00217412 2014-06-17

Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia

National Cancer Institute (NCI)

Phase 1 Completed
60 enrolled
CNSLymphoidOther hematologic neoplasmSarcoma

Burkitt Lymphoma, Medulloblastoma, Neuroblastoma, Recurrence, Lymphoma, Large B-Cell, Diffuse, Rhabdoid Tumor, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile, Dendritic Cell Sarcoma, Interdigitating

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