Announcements Trials
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Phase

Phase 2 4Phase 3 2Phase NA 1Phase EARLY_PHASE1 1Phase 2/3 1Phase 1/2 1Phase 1 1

Status

Terminated 2Active not recruiting 2

Sponsor Class

OTHER 2NETWORK 2

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 4

Conditions

Glioblastoma 18Brain Neoplasms 8Lymphoma 6Central Nervous System Neoplasms 6Medulloblastoma 4Glioma 4Astrocytoma 4Recurrence 3Neoplasms 2Lymphoma, Non-Hodgkin 2Lymphoma, AIDS-Related 2Lung Neoplasms 2Uveal Melanoma 1Spinal Cord Neoplasms 1Solid Tumor 1Sarcoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pancreatic Neoplasms 1Oligodendroglioma 1Neoplasm Metastasis 1Melanoma 1Lymphoma, Mantle-Cell 1Lymphoma, Large-Cell, Immunoblastic 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, Follicular 1Leukemia-Lymphoma, Adult T-Cell 1Kidney Neoplasms 1Intraocular Lymphoma 1Hereditary Sensory and Autonomic Neuropathies 1Gliosarcoma 1

Interventions

Cyclophosphamide 18Etoposide 12Cisplatin 11Temozolomide 10Vincristine 9Radiotherapy 9Magnetic Resonance Spectroscopy 9Filgrastim 8Irinotecan 7Carboplatin 7X-Rays 6Phantoms, Imaging 6Topotecan 5Specimen Handling 5Peripheral Blood Stem Cell Transplantation 5Nuclear Medicine Department, Hospital 5Thiotepa 4Radiation 4Lomustine 4Biopsy 4Bevacizumab 4tipifarnib 3sargramostim 3palbociclib 3Methotrexate 3HhAntag691 3Chemotherapy, Adjuvant 3ulixertinib 2tazemetostat 2sonidegib 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 2 × Medulloblastoma × Lomustine × Clear all
NCT02724579 2026-05-20

Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma

Children's Oncology Group

Phase 2 Active not recruiting
45 enrolled
CNS

Medulloblastoma

NCT04049669 2026-01-08

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG

Augusta University

Phase 2 Active not recruiting
130 enrolled
CNS

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Ependymoma, Glioblastoma, Medulloblastoma

NCT04402073 2025-10-23

PersoMed-I

European Organisation for Research and Treatment of Cancer - EORTC

Phase 2 Terminated
20 enrolled
CNS

Medulloblastoma

NCT00031590 2019-04-25

Low-Dose Radiation and Combination Chemotherapy Following Surgery in Children With Newly Diagnosed Medulloblastoma

Children's Hospital of Philadelphia

Phase 2 Terminated
30 enrolled 5 charts
CNS

Brain Neoplasms, Medulloblastoma, Central Nervous System Neoplasms

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