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Phase

Phase 1/2 1Phase 1 1

Status

Unknown 1Terminated 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2

Conditions

Brain Neoplasms 3Supratentorial Neoplasms 2Oligodendroglioma 2Medulloblastoma 2Kidney Neoplasms 2Central Nervous System Neoplasms 2Astrocytoma 2Urinary Bladder Neoplasms 1Prostatic Neoplasms 1Postoperative Complications 1Optic Nerve Glioma 1Neuroectodermal Tumors, Primitive 1Neoplasms, Germ Cell and Embryonal 1Nasopharyngeal Carcinoma 1Intracranial Hypertension 1Hemorrhage 1Gliosarcoma 1Glioma 1Glioblastoma 1Familial ependymoma 1Drug-Related Side Effects and Adverse Reactions 1Carcinoma, Renal Cell 1Breast Neoplasms 1

Interventions

Cyclophosphamide 20Etoposide 19Temozolomide 16Carboplatin 16Filgrastim 15Vincristine 11Cisplatin 11Radiotherapy 10Thiotepa 9Melphalan 8Granulocyte Colony-Stimulating Factor 8etoposide phosphate 7Lomustine 7Peripheral Blood Stem Cell Transplantation 6Radiation 5Methotrexate 5Magnetic Resonance Spectroscopy 5Topotecan 4Mesna 4Gemcitabine 4Busulfan 4sargramostim 3gallium Ga 68 dotatate 3Thalidomide 3Stem Cell Transplantation 3Irinotecan 3Ifosfamide 3Donepezil 3Celecoxib 3Automobiles 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
OTHER × Medulloblastoma × Mannitol × Clear all
NCT00983398 2021-10-26

Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors

OHSU Knight Cancer Institute

Phase 1/2 Unknown
17 enrolled
CNS

Medulloblastoma, Neoplasms, Germ Cell and Embryonal, Neuroectodermal Tumors, Primitive

NCT00238173 2017-04-21

Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors

OHSU Knight Cancer Institute

Phase 1 Terminated
2 enrolled
CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Optic Nerve Glioma, Drug-Related Side Effects and Adverse Reactions

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