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Phase

Phase 1 1

Status

Completed 5Withdrawn 1Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 9Leukemia, Myeloid, Acute 8Leukemia 8Lymphoma 7Myelodysplastic Syndromes 5Leukemia, Myeloid, Chronic-Phase 5Graft vs Host Disease 5Central Nervous System Neoplasms 5Leukemia, Myeloid, Accelerated Phase 4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Lymphoma, Non-Hodgkin 3Lymphoma, Large B-Cell, Diffuse 3Leukemia, Myelogenous, Chronic, BCR-ABL Positive 3Leukemia, Lymphocytic, Chronic, B-Cell 3Leukemia, Biphenotypic, Acute 3Burkitt Lymphoma 3Breast Neoplasms 3Waldenstrom Macroglobulinemia 2Sezary Syndrome 2Primary Myelofibrosis 2Myeloproliferative Disorders 2Mycosis Fungoides 2Lymphoma, T-Cell, Cutaneous 2Lymphoma, Mantle-Cell 2Lymphoma, Large-Cell, Immunoblastic 2Lymphoma, Large-Cell, Anaplastic 2Lymphoma, Follicular 2Lymphoma, Extranodal NK-T-Cell 2Lymphoma, B-Cell, Marginal Zone 2Leukemia, Myelomonocytic, Chronic 2

Interventions

Magnetic Resonance Spectroscopy 32-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 2thymoglobulin 1gallium Ga 68 dotatate 1fludarabine phosphate 1arginyllysine 1Whole Body Imaging 1Valproic Acid 1Thiotepa 1Temozolomide 1Tacrolimus 1Stem Cell Transplantation 1Nivolumab 1N(alpha)-(4-amino-4-deoxypteroyl)-N(delta)-hemiphthaloyl-L-ornithine 1Mycophenolic Acid 1Methotrexate 1Melphalan 1LY2940680 1Hematopoietic Stem Cell Transplantation 1Gadolinium DTPA 1Etoposide 1Erlotinib Hydrochloride 1Drug Therapy 1Biopsy 1Bandages 1Azacitidine 1Antilymphocyte Serum 1Amino Acids 190Y-octreotide, DOTA-Tyr(3)- 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Withdrawn × Medulloblastoma × Methotrexate × Clear all
NCT06466798 2026-01-08

Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies

The University of Texas Health Science Center, Houston

Phase 1 Withdrawn
CNS

Ependymoma, Medulloblastoma, Central Nervous System Neoplasms

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