Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Terminated 1Active not recruiting 1

Sponsor Class

OTHER 4INDUSTRY 2NIH 1NETWORK 1

Study Type

Interventional 2

Sponsor

Cancer Type

Sarcoma 2CNS 2

Conditions

Small Cell Lung Carcinoma 42Ovarian Neoplasms 33Fallopian Tube Neoplasms 15Neoplasms 12Carcinoma, Ovarian Epithelial 10Uterine Cervical Neoplasms 7Recurrence 6Neuroblastoma 5Lung Neoplasms 5Neoplasm Metastasis 4Carcinoma, Non-Small-Cell Lung 4Sarcoma, Ewing 3Endometrial Neoplasms 3Uterine Cervical Dysplasia 2Sarcoma, Clear Cell 2Sarcoma 2Rhabdomyosarcoma 2Myoepithelioma 2Medulloblastoma 2Liposarcoma, Myxoid 2Histiocytoma, Angiomatoid Fibrous 2Hereditary Sensory and Autonomic Neuropathies 2Diffuse Intrinsic Pontine Glioma 2Desmoplastic Small Round Cell Tumor 2Chondrosarcoma, Extraskeletal Myxoid 2Carcinoma 2Solid Tumours 1Solid Tumors 1Solid Tumor 1SCLC 1

Interventions

Temozolomide 6sonidegib 4Irinotecan 3Topotecan 2LY2940680 2Cyclophosphamide 2ribociclib 1pomalidomide 1palbociclib 1omburtamab I-131 1exatecan 1entrectinib 1dinutuximab 1bempegaldesleukin 1abemaciclib 1TB-403 1Pemetrexed 1ONC206 1Nivolumab 1NVP-LEQ506 1Granulocyte-Macrophage Colony-Stimulating Factor 1Filgrastim 1Fentanyl 1Etoposide 1CLR1404 1Biological Factors 190Y-octreotide, DOTA-Tyr(3)- 11-methyltryptophan 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
INDUSTRY × Medulloblastoma × Topotecan × Clear all
NCT05429502 2025-10-10

Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors

Novartis

Phase 1 Terminated
12 enrolled
CNSSarcoma

Glioma, Medulloblastoma, Neuroblastoma, Recurrence, Rhabdomyosarcoma

NCT03709680 2025-01-14

Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors

Pfizer

Phase 2 Active not recruiting
128 enrolled
CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Bone Neoplasms, Medulloblastoma, Neoplasms, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Rhabdoid Tumor

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