Announcements Trials
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Phase

Phase 1 2

Status

Withdrawn 1Completed 1

Sponsor Class

OTHER 1NETWORK 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2

Conditions

Brain Neoplasms 4Sarcoma 3Neoplasms 3Recurrence 2Ovarian Neoplasms 2Neoplasm Metastasis 2Nasopharyngeal Carcinoma 2Medulloblastoma 2Glioblastoma 2Central Nervous System Neoplasms 2Breast Neoplasms 2Astrocytoma 2Urologic Neoplasms 1Thyroid Neoplasms 1Spinal Cord Neoplasms 1Solid Tumors 1Solid Tumor Malignancies 1Soft Tissue Neoplasms 1Pharyngeal Neoplasms 1Osteosarcoma 1Optic Nerve Glioma 1Neurofibromatosis 2 1Neuroectodermal Tumors, Primitive, Peripheral 1Neuroectodermal Tumors, Primitive 1Neuroectodermal Tumors 1Neuroblastoma 1Neoplasms, Mesothelial 1Myelodysplastic Syndromes 1Multiple Acyl Coenzyme A Dehydrogenase Deficiency 1Mouth Neoplasms 1

Interventions

Temozolomide 15Filgrastim 13Cyclophosphamide 9Carboplatin 9Granulocyte Colony-Stimulating Factor 7Etoposide 7Thiotepa 5Peripheral Blood Stem Cell Transplantation 5Melphalan 5Vorinostat 4Busulfan 4sonidegib 3ribociclib 3Vincristine 3Topotecan 3O(6)-benzylguanine 3Magnetic Resonance Spectroscopy 3Irinotecan 3Automobiles 3veliparib 2sargramostim 2pembrolizumab 2fludarabine 2etoposide phosphate 2Valproic Acid 2Thalidomide 2Surgical Procedures, Operative 2Stem Cell Transplantation 2Specimen Handling 2Radiotherapy, Intensity-Modulated 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Medulloblastoma × Valproic Acid × Clear all
NCT01861990 2015-05-22

Valproic Acid in Childhood Progressive Brain Tumors

Medical University of South Carolina

Phase 1 Withdrawn
CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Medulloblastoma, Neuroectodermal Tumors, Primitive

NCT00107458 2014-08-07

Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors

Children's Oncology Group

Phase 1 Completed
26 enrolled
CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Optic Nerve Glioma

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