Announcements Trials
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Phase

Phase EARLY_PHASE1 1Phase 3 1Phase 2 1

Status

Completed 11Active not recruiting 5Terminated 3Recruiting 3

Sponsor Class

OTHER 2NETWORK 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 19Burkitt Lymphoma 17Lymphoma, Large B-Cell, Diffuse 12Neuroblastoma 7Lymphoma, Follicular 7Lymphoma, B-Cell 7Leukemia, Biphenotypic, Acute 7Rhabdomyosarcoma 6Lymphoma, T-Cell, Peripheral 6Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 5Sarcoma, Ewing 4Lymphoma 4Retinoblastoma 3Recurrence 3Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 3Osteosarcoma 3Medulloblastoma 3Lymphoma, T-Cell 3Lymphoma, Non-Hodgkin 3Wilms Tumor 2Sarcoma 2Plasmablastic Lymphoma 2Lymphoma, B-Cell, Marginal Zone 2Leukemia, B-Cell 2Hodgkin Disease 2Ganglioneuroblastoma 2Blastic Plasmacytoid Dendritic Cell Neoplasm 2Stage I Mixed Cell Type Kidney Wilms Tumor 1Rhabdomyosarcoma, Embryonal 1Rhabdoid Tumor 1

Interventions

Cyclophosphamide 6Temozolomide 5Etoposide 5Vincristine 3Radiotherapy 3Cisplatin 3lutetium Lu 177 dotatate 2etoposide phosphate 2Radiation 2Filgrastim 2Celecoxib 2Carboplatin 2sodium thiosulfate 1ribociclib 1pegfilgrastim 1palbociclib 1olaparib 1ibrutinib 1fludarabine 1fenofibric acid 1abemaciclib 1Topotecan 1Thiotepa 1Thalidomide 1Tamoxifen 1Tablets 1Standard of Care 1Specimen Handling 1Platinum 1ONC206 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Recruiting × Medulloblastoma × Vincristine × Clear all
NCT05382338 2026-05-05

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

Children's Oncology Group

Phase 3 Recruiting
225 enrolled
CNS

Medulloblastoma

NCT06942039 2026-02-27

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

C17 Council

Phase EARLY_PHASE1 Recruiting
15 enrolled
CNS

Medulloblastoma, Neuroblastoma, Pinealoma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor, Pyloric Stenosis, Hypertrophic

NCT05535166 2026-02-12

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

St. Jude Children's Research Hospital

Phase 2 Recruiting
130 enrolled
CNS

Brain Neoplasms, Medulloblastoma

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