Announcements Trials
Browse Landscape

Phase

Phase 1 3

Status

Recruiting 2Completed 1

Sponsor Class

INDUSTRY 3

Study Type

Interventional 3

Sponsor

Cancer Type

Dermatologic 3Thoracic 2Head & Neck 2Gynecologic 1Genitourinary 1Gastrointestinal 1CNS 1Breast 1

Conditions

Colorectal Neoplasms 82Squamous Cell Carcinoma of Head and Neck 53Carcinoma, Non-Small-Cell Lung 29Head and Neck Neoplasms 27Colonic Neoplasms 23Neoplasm Metastasis 17Neoplasms 16Rectal Neoplasms 15Pancreatic Neoplasms 10Lung Neoplasms 10Mouth Neoplasms 8Carcinoma, Squamous Cell 8Laryngeal Neoplasms 7Hypopharyngeal Neoplasms 7Oropharyngeal Neoplasms 6Carcinoma 6Solid Tumors 5Parkinson Disease 4, Autosomal Dominant Lewy Body 5Gastrointestinal Neoplasms 5Breast Neoplasms 5Tongue Neoplasms 4Ovarian Neoplasms 4Endometrial Neoplasms 4Thyroid Neoplasms 3Recurrence 3Melanoma 3Digestive System Neoplasms 3Colorectal Cancer Metastatic 3Carcinoma, Renal Cell 3Carcinoma, Pancreatic Ductal 3

Interventions

pembrolizumab 141Nivolumab 117Ipilimumab 69Cyclophosphamide 34Specimen Handling 29Magnetic Resonance Spectroscopy 27trametinib 23binimetinib 22fludarabine 21Interleukin-2 21dabrafenib 19relatlimab 17encorafenib 17CTLA-4 Antigen 17Biopsy 17aldesleukin 16cemiplimab 15atezolizumab 15Radiosurgery 15fludarabine phosphate 14Opdualag 14lifileucel 10lenvatinib 10Radiotherapy 10Blood Specimen Collection 10Paclitaxel 9Pemetrexed 8Cisplatin 8Carboplatin 8Bevacizumab 8

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Melanoma × Cetuximab × 1 year × Clear all
NCT05355701 2026-05-14

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

Pfizer

Phase 1 Recruiting
267 enrolled
CNSDermatologicHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Glioma, Melanoma, Thyroid Neoplasms

NCT04485013 2026-02-18

TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers

Tizona Therapeutics, Inc

Phase 1 Recruiting
240 enrolled
BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Adenocarcinoma of Lung, Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT05668585 2025-11-21

A Study to Characterize the Safety, Tolerability, and Preliminary Efficacy of CFT1946 as Monotherapy and Combination Therapy in Subjects With BRAF V600 Mutant Solid Tumors

C4 Therapeutics, Inc.

Phase 1 Completed
89 enrolled
Dermatologic

Melanoma

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