Clinical Trials Browser

Melanoma

NCT03276832 2026-03-19

Imiquimod and Pembrolizumab in Treating Patients With Stage IIIB-IV Melanoma

Phase EARLY_PHASE1 Completed

7 enrolled 11 charts

Dermatologic

Melanoma

NCT04119024 2026-03-17

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

Phase 1 Recruiting

18 enrolled

BreastCNSDermatologicEndocrineHead & NeckNETThoracic

Adenocarcinoma of Lung, Squamous Cell Carcinoma of Head and Neck, Uveal Melanoma, Breast Neoplasms, Adenoma, Islet Cell, Melanoma, Neoplasm Metastasis, Paraganglioma, Pheochromocytoma, Thyroid Neoplasms, Adrenocortical Carcinoma, Neuroendocrine Tumors

NCT05098210 2026-03-12

Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer

Phase 1 Recruiting

25 enrolled

DermatologicThoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Melanoma, Neoplasm Metastasis

NCT05269381 2026-03-12

PNeoVCA

Phase 1/2 Recruiting

132 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Carcinosarcoma, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Carcinoma, Merkel Cell, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT06626256 2025-12-24

STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

Phase 1 Withdrawn

DermatologicGastrointestinalGenitourinaryGynecologic

Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms, Colorectal Neoplasms

NCT05393713 2025-12-03

Intra-Lymphatic STI-3031 Using the Sofusa DoseConnect Device for Treatment of In-Transit Melanoma, The Sofusa-2 Study

Phase 1 Terminated

3 enrolled

Dermatologic

Melanoma

NCT07155317 2025-11-12

Time-of-Day Specified Immunotherapy for Advanced Melanoma, The TIME Trial

Phase 2 Recruiting

99 enrolled

Dermatologic

Melanoma

NCT00386906 2025-05-07

Sentinel Lymph Node (SLN) Biopsy for Conjunctival/Eyelid Melanoma

Phase 1 Completed

38 enrolled

Dermatologic

Eye Diseases, Melanoma

NCT03412058 2025-02-20

CHECK'UP

Phase NA Active not recruiting

670 enrolled

DermatologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Melanoma

NCT03757689 2025-02-11

Neoadjuvant PD-1 Blockade in Patients with Stage IIB/C Melanoma

Phase 2 Active not recruiting

63 enrolled

Dermatologic

Melanoma

NCT05764395 2024-10-10

Rigosertib Plus Pembrolizumab in Treating Patients With Unresectable/Metastatic Melanoma Refractory to PD-1 Inhibitors

Phase 2 Suspended

29 enrolled

Dermatologic

Melanoma

NCT02977052 2023-11-15

OpACIN-neo

Phase 2 Unknown

186 enrolled

Dermatologic

Melanoma

NCT05906277 2023-06-15

Melamoma4p

Phase NA Unknown

300 enrolled

Dermatologic

Melanoma

NCT02414750 2022-11-30

REPOSIT

Phase 2 Terminated

78 enrolled

Dermatologic

Melanoma

NCT00945269 2022-11-15

Therapeutic Autologous Lymphocytes, Aldesleukin, and Denileukin Diftitox in Treating Patients With Stage III-IV Melanoma

Phase 1/2 Terminated

3 enrolled

Dermatologic

Melanoma

NCT01328535 2020-10-22

Individualized Temozolomide in Treating Patients With Stage IV Melanoma That Cannot Be Removed By Surgery

Phase 2 Completed

25 enrolled 8 charts

Dermatologic

Melanoma

NCT04493723 2020-07-30

Serial Tumour Biopsies and Blood Biomarkers in Melanoma

Recruiting

300 enrolled

Dermatologic

Melanoma

NCT02654821 2018-11-02

TCR

Phase 1/2 Unknown

12 enrolled

Dermatologic

Uveal Melanoma, Melanoma

NCT00568763 2018-10-31

Radiofrequency Therapy-Induced Endogenous Heat-Shock Proteins With or Without Radiofrequency Ablation or Cryotherapy in Treating Patients With Stage IV Melanoma

Phase 1 Completed

11 enrolled

Dermatologic

Melanoma

NCT00715793 2017-10-03

UPCI-07-008

Phase 1/2 Completed

39 enrolled 12 charts

Dermatologic

Melanoma, Neoplasm Metastasis, Skin Neoplasms

NCT02625337 2017-09-15

IMPemBra

Phase 2 Unknown

32 enrolled

Dermatologic

Melanoma

NCT00871481 2017-04-19

Laboratory-Treated T Cells and Ipilimumab in Treating Patients With Metastatic Melanoma

Phase 1/2 Completed

10 enrolled

Dermatologic

Melanoma

NCT00553306 2017-02-15

Laboratory-Treated T Cells and Aldesleukin After Cyclophosphamide in Treating Patients With Stage IV Melanoma

Phase 1/2 Completed

10 enrolled

Dermatologic

Melanoma

NCT00705640 2016-12-16

Mel48

Phase 1 Completed

45 enrolled

Dermatologic

Uveal Melanoma, Melanoma

NCT02938728 2016-10-25

PREDIMEL

Unknown

120 enrolled

Dermatologic

Melanoma

NCT01316692 2016-05-30

Aurora A Kinase Inhibitor MLN8237 in Treating Patients With Unresectable Stage III-IV Melanoma

Phase 2 Terminated

12 enrolled 10 charts

Dermatologic

Melanoma

NCT00900302 2016-02-10

OX-40 Protein Expression in the Sentinel Lymph Nodes of Patients With Cancer

Completed

98 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Anus Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Melanoma, Neoplasms, Neoplasms, Unknown Primary, Penile Neoplasms, Salivary Gland Neoplasms, Skin Neoplasms, Vulvar Neoplasms, Breast Neoplasms, Male

NCT00661336 2015-03-13

A Phase I Trial of Normothermic Isolated Limb Infusion (ILI) With Melphalan Plus Buthionine Sulfoximine (BSO) in Patients With Locally Advanced Malignant Melanoma

Phase 1 Withdrawn

Dermatologic

Melanoma

NCT00824889 2014-08-29

Exploratory Study of Natural Killer Cells in Human Skin

Phase NA Completed

28 enrolled

Dermatologic

Dermatitis, Atopic, Dermatitis, Contact, Graft vs Host Disease, Lichen Planus, Melanoma, Psoriasis

NCT00466687 2013-07-22

Erlotinib and Bevacizumab in Treating Patients With Stage IV Melanoma

Phase 2 Completed

34 enrolled 10 charts

Dermatologic

Melanoma

NCT00438984 2012-03-16

Therapeutic Autologous Lymphocytes, Cyclophosphamide, and Aldesleukin in Treating Patients With Stage IV Melanoma

Phase 1 Completed

11 enrolled

Dermatologic

Melanoma

NCT01106235 2011-12-21

Therapeutic Autologous Lymphocytes, Cyclophosphamide, and Aldesleukin in Treating Patients With Metastatic Melanoma

Phase 1 Terminated

12 enrolled

Dermatologic

Melanoma

NCT00602199 2011-05-16

ABT-510 in Treating Patients With Metastatic Melanoma

Phase 2 Completed

42 enrolled

Dermatologic

Melanoma

Clinical Trials

Peripheral T Cell Determinants of Response and Resistance to Pembrolizumab in Melanoma

Imiquimod and Pembrolizumab in Treating Patients With Stage IIIB-IV Melanoma

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer

PNeoVCA

STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

Intra-Lymphatic STI-3031 Using the Sofusa DoseConnect Device for Treatment of In-Transit Melanoma, The Sofusa-2 Study

Time-of-Day Specified Immunotherapy for Advanced Melanoma, The TIME Trial

Sentinel Lymph Node (SLN) Biopsy for Conjunctival/Eyelid Melanoma

CHECK'UP

Neoadjuvant PD-1 Blockade in Patients with Stage IIB/C Melanoma

Rigosertib Plus Pembrolizumab in Treating Patients With Unresectable/Metastatic Melanoma Refractory to PD-1 Inhibitors

OpACIN-neo

Melamoma4p

REPOSIT

Therapeutic Autologous Lymphocytes, Aldesleukin, and Denileukin Diftitox in Treating Patients With Stage III-IV Melanoma

Individualized Temozolomide in Treating Patients With Stage IV Melanoma That Cannot Be Removed By Surgery

Serial Tumour Biopsies and Blood Biomarkers in Melanoma

TCR

Radiofrequency Therapy-Induced Endogenous Heat-Shock Proteins With or Without Radiofrequency Ablation or Cryotherapy in Treating Patients With Stage IV Melanoma

UPCI-07-008

IMPemBra

Laboratory-Treated T Cells and Ipilimumab in Treating Patients With Metastatic Melanoma

Laboratory-Treated T Cells and Aldesleukin After Cyclophosphamide in Treating Patients With Stage IV Melanoma

Mel48

PREDIMEL

Aurora A Kinase Inhibitor MLN8237 in Treating Patients With Unresectable Stage III-IV Melanoma

OX-40 Protein Expression in the Sentinel Lymph Nodes of Patients With Cancer

A Phase I Trial of Normothermic Isolated Limb Infusion (ILI) With Melphalan Plus Buthionine Sulfoximine (BSO) in Patients With Locally Advanced Malignant Melanoma

Exploratory Study of Natural Killer Cells in Human Skin

Erlotinib and Bevacizumab in Treating Patients With Stage IV Melanoma

Therapeutic Autologous Lymphocytes, Cyclophosphamide, and Aldesleukin in Treating Patients With Stage IV Melanoma

Therapeutic Autologous Lymphocytes, Cyclophosphamide, and Aldesleukin in Treating Patients With Metastatic Melanoma

ABT-510 in Treating Patients With Metastatic Melanoma