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Phase

Phase 1 2Phase 2 1Phase 1/2 1

Status

Terminated 4Withdrawn 2Completed 1

Sponsor Class

NIH 3OTHER 1

Study Type

Interventional 4

Sponsor

Cancer Type

Dermatologic 4Sarcoma 3Thoracic 1

Conditions

Colorectal Neoplasms 8Breast Neoplasms 8Neoplasm Metastasis 7Lung Neoplasms 6Rectal Neoplasms 5Sarcoma 4Prostatic Neoplasms 4Melanoma 4Colonic Neoplasms 4Pancreatic Neoplasms 3Ovarian Neoplasms 3Esophageal Neoplasms 3Carcinoma, Non-Small-Cell Lung 3Thymoma 2Neoplasms 2Mouth Neoplasms 2Head and Neck Neoplasms 2Carcinoma 2Adenomatous Polyposis Coli 2Uterine Neoplasms 1Unspecified Adult Solid Tumor, Protocol Specific 1Triple Negative Breast Neoplasms 1Thrombocytosis 1Stomach Neoplasms 1Recurrence 1Primary Myelofibrosis 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Paranasal Sinus Neoplasms 1Papilloma 1Pain 1

Interventions

pembrolizumab 51Ipilimumab 50Cyclophosphamide 43Nivolumab 41aldesleukin 30Interleukin-2 23Vemurafenib 20fludarabine 19Temozolomide 18fludarabine phosphate 15dabrafenib 15trametinib 12spartalizumab 10Radiotherapy 10Radiosurgery 10Dacarbazine 10CTLA-4 Antigen 10cobimetinib 9binimetinib 9poly ICLC 7encorafenib 7Paclitaxel 7atezolizumab 6Introns 6Biopsy 6montanide ISA 51 5Carboplatin 5epacadostat 4MART-1 Antigen 4Interferon alpha-2 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Terminated × Melanoma × Celecoxib × Clear all
NCT04093323 2026-02-25

Polarized Dendritic Cell (aDC1) Based Treatment, Interferon Alpha-2, Rintatolimod, and Celecoxib for the Treatment of HLA-A2+ Refractory Melanoma

Roswell Park Cancer Institute

Phase 2 Terminated
1 enrolled
Dermatologic

Melanoma

NCT02054104 2022-01-26

Adjuvant Tumor Lysate Vaccine and Iscomatrix With or Without Metronomic Oral Cyclophosphamide and Celecoxib in Patients With Malignancies Involving Lungs, Esophagus, Pleura, or Mediastinum

National Institutes of Health Clinical Center (CC)

Phase 1/2 Terminated
21 enrolled 11 charts
DermatologicSarcoma

Melanoma, Sarcoma, Neoplasm, Residual

NCT01313429 2020-03-03

Tumor Cell Vaccine for Patients Undergoing Surgery for Sarcomas, Melanomas, Germ Cell Tumors, or Malignancies That Have Metastasized to the Lungs, Pleura, or Mediastinum

National Institutes of Health Clinical Center (CC)

Phase 1 Terminated
19 enrolled
DermatologicSarcomaThoracic

Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Sarcoma

NCT01341496 2018-07-05

Tumor Cell Vaccines and ISCOMATRIX With Chemotherapy After Tumor Removal

National Institutes of Health Clinical Center (CC)

Phase 1 Terminated
41 enrolled
DermatologicSarcoma

Melanoma, Neoplasm Metastasis, Sarcoma

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