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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Dermatologic 1

Conditions

Burkitt Lymphoma 7Meningeal Carcinomatosis 5Lung Neoplasms 5Carcinoma, Non-Small-Cell Lung 5Breast Neoplasms 4Leukemia, Myeloid, Acute 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Meningeal Neoplasms 2Lymphoma, Large B-Cell, Diffuse 2Uveal Melanoma 1Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 1Nevus 1Melanoma 1Lymphoma, T-Cell 1Lymphoma, Mantle-Cell 1Leukemia, Myelomonocytic, Juvenile 1Leukemia, Monocytic, Acute 1Leukemia, Hairy Cell 1Leukemia, Biphenotypic, Acute 1Hematopoietic and Lymphatic System Neoplasm 1Germinoma 1Down Syndrome 1Diabetes Insipidus 1Brain Neoplasms 1

Interventions

pembrolizumab 54Nivolumab 50Ipilimumab 28Cyclophosphamide 16binimetinib 10Specimen Handling 10Magnetic Resonance Spectroscopy 10fludarabine 9Radiosurgery 9relatlimab 8encorafenib 8Opdualag 8Biopsy 8aldesleukin 7Interleukin-2 7atezolizumab 6Immunotherapy 6Blood Specimen Collection 6cemiplimab 5CTLA-4 Antigen 5Bevacizumab 5trametinib 4fludarabine phosphate 4dabrafenib 4Temozolomide 4Paclitaxel 4Immune Checkpoint Inhibitors 4spartalizumab 3Surgical Procedures, Operative 3Metformin 3

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Recruiting × Melanoma × Spinal Puncture × Clear all
NCT03025256 2026-05-05

Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease

M.D. Anderson Cancer Center

Phase 1 Recruiting
75 enrolled
DermatologicThoracic

Uveal Melanoma, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Melanoma, Meningeal Neoplasms, Nevus

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