Announcements Trials
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Phase

Phase 1 1

Status

Terminated 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Gynecologic 1Genitourinary 1Dermatologic 1Breast 1

Conditions

Ovarian Neoplasms 21Neoplasms 16Neuroblastoma 14Small Cell Lung Carcinoma 13Carcinoma, Ovarian Epithelial 12Fallopian Tube Neoplasms 11Precursor Cell Lymphoblastic Leukemia-Lymphoma 10Lung Neoplasms 10Recurrence 8Leukemia 8Leukemia, Myeloid, Acute 7Uterine Cervical Neoplasms 6Unspecified Adult Solid Tumor, Protocol Specific 6Neoplasm Metastasis 6Lymphoma 6Sarcoma, Ewing 5Endometrial Neoplasms 5Carcinoma, Non-Small-Cell Lung 5Brain Neoplasms 5Sarcoma 4Lymphoma, Follicular 4Glioma 4Central Nervous System Neoplasms 4Burkitt Lymphoma 4Blast Crisis 4Rhabdomyosarcoma 3Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Myelodysplastic Syndromes 3Meningeal Carcinomatosis 3Medulloblastoma 3

Interventions

pembrolizumab 92Nivolumab 56Ipilimumab 55Cyclophosphamide 52Vemurafenib 28fludarabine 27aldesleukin 25Interleukin-2 25fludarabine phosphate 21trametinib 20dabrafenib 17Temozolomide 14Biopsy 14Cisplatin 13spartalizumab 12atezolizumab 12Carboplatin 11cobimetinib 10Specimen Handling 10Paclitaxel 10Introns 10CTLA-4 Antigen 10poly ICLC 9binimetinib 9Radiotherapy 9Radiosurgery 9MART-1 Antigen 9tremelimumab 8incomplete Freund's adjuvant 8Radiation 8

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1 × Melanoma × Topotecan × Clear all
NCT02419495 2025-06-04

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

M.D. Anderson Cancer Center

Phase 1 Terminated
221 enrolled
BreastDermatologicGenitourinaryGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Triple Negative Breast Neoplasms

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