Clinical Trials

Phase 3 Not yet recruiting

Melanoma

NCT07068074 2025-11-13

A Randomized Phase III Study of Management of Treatment Naive Primary Melanoma in Elderly Patients

428 enrolled

Phase 2 Active not recruiting

Melanoma

NCT04511013 2025-09-11

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

Phase 2 Recruiting

112 enrolled

CNSDermatologic

Brain Neoplasms, Melanoma

NCT07130032 2025-08-19

reICB

Phase 2 Recruiting

90 enrolled

DermatologicThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma

NCT03235245 2025-08-01

EBIN

271 enrolled

Phase 2 Not yet recruiting

Melanoma

NCT07040280 2025-06-27

Testing the Effect of Sulforaphane, a Compound Naturally Found in Cruciferous Vegetables, on Preventing Melanoma in Patients With a Prior History of Melanoma

120 enrolled

DermatologicGastrointestinalGenitourinaryHead & NeckSarcoma

Melanoma, Skin Neoplasms

NCT04498767 2024-08-26

OligoRARE

Phase NA Recruiting

200 enrolled

Urinary Bladder Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Melanoma, Pancreatic Neoplasms, Sarcoma, Skin Neoplasms, Stomach Neoplasms

NCT01942603 2023-11-28

Minitub

Active not recruiting

296 enrolled

Melanoma

NCT02740920 2023-08-25

Response to Pembrolizumab in Metastatic Melanoma: Computed Tomography Texture Analysis as a Predictive Biomarker

9 enrolled 8 charts

Melanoma

NCT01152788 2023-08-22

Phase II Study of Interleukin-21 (rIL-21) vs Dacarbazine (DTIC) in Patients With Metastatic or Recurrent Melanoma

64 enrolled 10 charts

Melanoma

NCT00053781 2023-08-04

Perifosine in Treating Patients With Metastatic or Recurrent Malignant Melanoma

18 enrolled

Melanoma

NCT00514085 2023-08-04

Interleukin-21 in Treating Patients With Metastatic or Recurrent Malignant Melanoma

40 enrolled

Melanoma

NCT00700882 2023-07-03

Dasatinib in Treating Patients With Locally Advanced or Metastatic Mucosal Melanoma, Acral Melanoma, or Vulvovaginal Melanoma That Cannot Be Removed By Surgery

81 enrolled 9 charts

Melanoma

NCT00049530 2023-06-29

PEG-Interferon Alfa-2b in Treating Patients With Stage IV Melanoma

32 enrolled 8 charts

Melanoma

NCT00071981 2023-06-28

Vaccine Therapy Using Melanoma Peptides for Cytotoxic T Cells and Helper T Cells in Treating Patients With Metastatic Melanoma

175 enrolled 12 charts

Melanoma

NCT00104884 2023-06-28

FR901228 in Treating Patients With Unresectable Stage III or Stage IV Malignant Melanoma

4 enrolled 4 charts

Melanoma

NCT00003027 2023-06-22

Combination Chemotherapy With or Without Interleukin-2 and Interferon Alfa in Treating Patients With Metastatic Melanoma

Phase 3 Completed

482 enrolled

Melanoma

NCT00003308 2023-06-22

Radiation Therapy in Treating Patients With Newly Diagnosed Brain Metastases From Kidney Cancer, Melanoma, or Sarcoma

CNSDermatologicGenitourinaryGynecologicSarcoma

Brain Neoplasms, Carcinoma, Renal Cell, Chondrosarcoma, Kidney Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Neuroectodermal Tumors, Primitive, Peripheral

NCT00003444 2023-06-22

Interferon Alfa-2b With or Without Radiation Therapy in Treating Patients With Melanoma That Has Metastasized to Lymph Nodes in the Neck, Under the Arm, or in the Groin

Phase 3 Completed

167 enrolled

Melanoma

NCT00003601 2023-06-18

Tretinoin With or Without Fenretinide in Treating Patients With Dysplastic Nevus Syndrome

38 enrolled

Melanoma

NCT02974803 2021-08-20

Concurrent Dabrafenib + Trametinib With Sterotactic Radiation in BRAF Mutation-Positive Malignant Melanoma and Brain Metastases

6 enrolled 3 charts

CNSDermatologic

Brain Neoplasms, Melanoma

NCT02177110 2020-11-17

SYS-ACT

16 enrolled

Melanoma

NCT00005971 2020-04-09

Flavopiridol in Treating Patients With Metastatic Malignant Melanoma

17 enrolled

Melanoma

NCT02507947 2018-07-09

SPECTAmel: Screening Patients With Melanoma Tumors for Efficient Clinical Trial Access

Withdrawn

Melanoma

NCT00898183 2018-06-28

S9431: Studying Genes and Immune Response in Tumor Samples From Patients With Locally Advanced or Metastatic Melanoma

91 enrolled

Melanoma

NCT00974610 2017-05-24

Study of Blood Samples From Patients With Malignant Melanoma, Metastatic Breast Cancer, Advanced Lung Cancer, Pancreatic Cancer, or Colorectal Cancer.

BreastDermatologicGastrointestinalThoracic

803 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Melanoma, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Breast Neoplasms, Male, Small Cell Lung Carcinoma

NCT00897520 2017-05-19

Biomarkers in Patients With High-Risk Melanoma Receiving High-Dose Interferon Therapy

40 enrolled

Melanoma

NCT00897546 2017-05-19

Biomarkers to Predict Response to Interferon Therapy in Patients With Melanoma

1,716 enrolled

Melanoma

NCT00937781 2017-05-17

Study of Tumor Tissue From Patients With Melanoma Treated on Clinical Trial EST-1690

307 enrolled

Melanoma

NCT01209299 2017-05-17

Biomarkers in Predicting Response to Chemotherapy in Patients With Advanced or Metastatic Melanoma Previously Treated With Carboplatin and Paclitaxel With or Without Sorafenib Tosylate

80 enrolled

Melanoma

NCT01388569 2017-05-17

Biomarkers in Blood Samples From Patients With Stage IV Melanoma Previously Treated With Sargramostim

48 enrolled

Melanoma

NCT01489423 2017-05-17

Tissue and Blood Biomarkers From Patients With Stage III or Stage IV Melanoma Treated With Ipilimumab With or Without Sargramostim

270 enrolled

Melanoma

NCT00897442 2016-10-28

Collecting Tumor Samples From Patients With Gynecological Tumors

DermatologicGynecologicOther solid neoplasmSarcomaThoracic

275 enrolled

Ovarian Germ Cell Cancer, Mesothelioma, Malignant, Brenner Tumor, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Melanoma, Ovarian Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Sarcoma, Endometrial Stromal, Gestational Trophoblastic Disease

NCT00093678 2015-10-08

Celecoxib in Managing Pain, Weight Loss, and Weakness in Patients With Advanced Cancer

Phase NA Withdrawn

DermatologicGynecologicLymphoidOther hematologic neoplasmSarcoma

AIDS-related Kaposi sarcoma, Burkitt Lymphoma, Cachexia, Chondrosarcoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Melanoma, Mycosis Fungoides, Ovarian Neoplasms, Pain, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Intraocular Lymphoma

NCT00006237 2015-03-25

S0008: Chemotherapy Plus Biological Therapy in Treating Patients With Melanoma

Phase 3 Completed

432 enrolled 7 charts

Melanoma

NCT00006249 2015-02-10

Interferon Alfa Following Surgery in Treating Patients With Stage III Melanoma

Phase 3 Unknown

1,258 enrolled

Melanoma

NCT00086866 2015-02-10

Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed With Surgery

Phase 2 Unknown

165 enrolled

Melanoma

NCT00755976 2014-12-31

Sulindac and Epirubicin in Treating Patients With Metastatic Malignant Melanoma

32 enrolled

CNSClassical hematologyDermatologicGenitourinaryGynecologicOther solid neoplasmSarcoma

Melanoma

NCT00003750 2014-08-08

Biological Therapy in Treating Children With Refractory or Recurrent Neuroblastoma or Other Tumors

Phase 1 Completed

28 enrolled

CNSDermatologicSarcoma

Melanoma, Neuroblastoma, Sarcoma, Osteosarcoma

NCT00003597 2014-07-24

Colony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid Tumors

Phase 1 Completed

16 enrolled

Uveal Melanoma, Astrocytoma, Carcinoma, Renal Cell, Medulloblastoma, Melanoma, Neoplasms, Wilms Tumor, Neuroblastoma, Neutropenia, Retinoblastoma, Osteosarcoma, Testicular Neoplasms, Thrombocytopenia, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma, Gestational Trophoblastic Disease

NCT00526149 2013-10-07

BI 2536 in Treating Patients With Recurrent or Metastatic Solid Tumors

BreastDermatologicGynecologicHead & NeckSarcoma

76 enrolled

Malignant mesenchymal tumor, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Breast Neoplasms, Fibrosarcoma, Head and Neck Neoplasms, Hemangiosarcoma, Leiomyosarcoma, Liposarcoma, Melanoma, Ovarian Neoplasms, Rhabdomyosarcoma, Sarcoma, Sarcoma, Synovial, Endometrial Neoplasms, Sarcoma, Endometrial Stromal, Sarcoma, Alveolar Soft Part, Neurofibrosarcoma, Histiocytoma, Malignant Fibrous, Desmoplastic Small Round Cell Tumor

NCT00003911 2013-01-31

S9903: Whole Brain Radiotherapy Followed By Stereotactic Radiosurgery for Limited Malignant Melanoma Brain Metastases