Clinical Trials

Phase 3 Not yet recruiting

Melanoma

NCT07068074 2025-11-13

A Randomized Phase III Study of Management of Treatment Naive Primary Melanoma in Elderly Patients

428 enrolled

Melanoma

NCT04511013 2025-09-11

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

Phase 2 Recruiting

112 enrolled

Phase 2 Active not recruiting

Brain Neoplasms, Melanoma

NCT07130032 2025-08-19

reICB

Phase 2 Recruiting

90 enrolled

DermatologicThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma

NCT03235245 2025-08-01

EBIN

271 enrolled

Phase 2 Not yet recruiting

Melanoma

NCT07040280 2025-06-27

Testing the Effect of Sulforaphane, a Compound Naturally Found in Cruciferous Vegetables, on Preventing Melanoma in Patients With a Prior History of Melanoma

120 enrolled

DermatologicGastrointestinalGenitourinaryHead & NeckSarcoma

Melanoma, Skin Neoplasms

NCT04498767 2024-08-26

OligoRARE

Phase NA Recruiting

200 enrolled

Urinary Bladder Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Melanoma, Pancreatic Neoplasms, Sarcoma, Skin Neoplasms, Stomach Neoplasms

NCT02740920 2023-08-25

Response to Pembrolizumab in Metastatic Melanoma: Computed Tomography Texture Analysis as a Predictive Biomarker

9 enrolled 8 charts

Melanoma

NCT01152788 2023-08-22

Phase II Study of Interleukin-21 (rIL-21) vs Dacarbazine (DTIC) in Patients With Metastatic or Recurrent Melanoma

64 enrolled 10 charts

Melanoma

NCT00053781 2023-08-04

Perifosine in Treating Patients With Metastatic or Recurrent Malignant Melanoma

18 enrolled

Melanoma

NCT00514085 2023-08-04

Interleukin-21 in Treating Patients With Metastatic or Recurrent Malignant Melanoma

40 enrolled

Melanoma

NCT00700882 2023-07-03

Dasatinib in Treating Patients With Locally Advanced or Metastatic Mucosal Melanoma, Acral Melanoma, or Vulvovaginal Melanoma That Cannot Be Removed By Surgery

81 enrolled 9 charts

Melanoma

NCT00049530 2023-06-29

PEG-Interferon Alfa-2b in Treating Patients With Stage IV Melanoma

32 enrolled 8 charts

Melanoma

NCT00071981 2023-06-28

Vaccine Therapy Using Melanoma Peptides for Cytotoxic T Cells and Helper T Cells in Treating Patients With Metastatic Melanoma

175 enrolled 12 charts

Melanoma

NCT00104884 2023-06-28

FR901228 in Treating Patients With Unresectable Stage III or Stage IV Malignant Melanoma

4 enrolled 4 charts

Melanoma

NCT00003027 2023-06-22

Combination Chemotherapy With or Without Interleukin-2 and Interferon Alfa in Treating Patients With Metastatic Melanoma

Phase 3 Completed

482 enrolled

Melanoma

NCT00003308 2023-06-22

Radiation Therapy in Treating Patients With Newly Diagnosed Brain Metastases From Kidney Cancer, Melanoma, or Sarcoma

CNSDermatologicGenitourinaryGynecologicSarcoma

Brain Neoplasms, Carcinoma, Renal Cell, Chondrosarcoma, Kidney Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Neuroectodermal Tumors, Primitive, Peripheral

NCT00003444 2023-06-22

Interferon Alfa-2b With or Without Radiation Therapy in Treating Patients With Melanoma That Has Metastasized to Lymph Nodes in the Neck, Under the Arm, or in the Groin

Phase 3 Completed

167 enrolled

Melanoma

NCT00003601 2023-06-18

Tretinoin With or Without Fenretinide in Treating Patients With Dysplastic Nevus Syndrome

38 enrolled

Melanoma

NCT02974803 2021-08-20

Concurrent Dabrafenib + Trametinib With Sterotactic Radiation in BRAF Mutation-Positive Malignant Melanoma and Brain Metastases

6 enrolled 3 charts

Brain Neoplasms, Melanoma

NCT00005971 2020-04-09

Flavopiridol in Treating Patients With Metastatic Malignant Melanoma

17 enrolled

DermatologicGynecologicLymphoidOther hematologic neoplasmSarcoma

Melanoma

NCT00093678 2015-10-08

Celecoxib in Managing Pain, Weight Loss, and Weakness in Patients With Advanced Cancer

Phase NA Withdrawn

AIDS-related Kaposi sarcoma, Burkitt Lymphoma, Cachexia, Chondrosarcoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Melanoma, Mycosis Fungoides, Ovarian Neoplasms, Pain, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Intraocular Lymphoma

NCT00006237 2015-03-25

S0008: Chemotherapy Plus Biological Therapy in Treating Patients With Melanoma

Phase 3 Completed

432 enrolled 7 charts

Melanoma

NCT00006249 2015-02-10

Interferon Alfa Following Surgery in Treating Patients With Stage III Melanoma

Phase 3 Unknown

1,258 enrolled

Melanoma

NCT00086866 2015-02-10

Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed With Surgery

Phase 2 Unknown

165 enrolled

Melanoma

NCT00755976 2014-12-31

Sulindac and Epirubicin in Treating Patients With Metastatic Malignant Melanoma

32 enrolled

CNSClassical hematologyDermatologicGenitourinaryGynecologicOther solid neoplasmSarcoma

Melanoma

NCT00003750 2014-08-08

Biological Therapy in Treating Children With Refractory or Recurrent Neuroblastoma or Other Tumors

Phase 1 Completed

28 enrolled

CNSDermatologicSarcoma

Melanoma, Neuroblastoma, Sarcoma, Osteosarcoma

NCT00003597 2014-07-24

Colony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid Tumors

Phase 1 Completed

16 enrolled

Uveal Melanoma, Astrocytoma, Carcinoma, Renal Cell, Medulloblastoma, Melanoma, Neoplasms, Wilms Tumor, Neuroblastoma, Neutropenia, Retinoblastoma, Osteosarcoma, Testicular Neoplasms, Thrombocytopenia, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma, Gestational Trophoblastic Disease

NCT00526149 2013-10-07

BI 2536 in Treating Patients With Recurrent or Metastatic Solid Tumors

BreastDermatologicGynecologicHead & NeckSarcoma

76 enrolled

Malignant mesenchymal tumor, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Breast Neoplasms, Fibrosarcoma, Head and Neck Neoplasms, Hemangiosarcoma, Leiomyosarcoma, Liposarcoma, Melanoma, Ovarian Neoplasms, Rhabdomyosarcoma, Sarcoma, Sarcoma, Synovial, Endometrial Neoplasms, Sarcoma, Endometrial Stromal, Sarcoma, Alveolar Soft Part, Neurofibrosarcoma, Histiocytoma, Malignant Fibrous, Desmoplastic Small Round Cell Tumor

NCT00003911 2013-01-31

S9903: Whole Brain Radiotherapy Followed By Stereotactic Radiosurgery for Limited Malignant Melanoma Brain Metastases

2 enrolled

Brain Neoplasms, Melanoma, Neoplasm Metastasis

NCT00020839 2012-09-24

Temozolomide With or Without Radiation Therapy to the Brain in Treating Patients With Stage IV Melanoma That Is Metastatic to the Brain

Phase 3 Terminated

23 enrolled

Brain Neoplasms, Melanoma, Neoplasm Metastasis

NCT00003828 2012-08-22

S9804: Vinorelbine in Treating Patients With Stage IV Melanoma

24 enrolled

Melanoma

NCT00104988 2012-08-22

S0508: Thalidomide and Temozolomide in Treating Patients With Stage IV Melanoma That Cannot Be Removed By Surgery

64 enrolled

Melanoma

NCT00014625 2012-07-24

E7070 in Treating Patients With Stage IV Melanoma

28 enrolled

Melanoma

NCT00085059 2012-07-18

Boron Neutron Capture Therapy Using Boronophenylalanine-Fructose Complex in Treating Patients With Metastatic Melanoma

4 enrolled

Melanoma

NCT00003989 2012-07-11

ISIS 3521 in Treating Patients With Advanced, Unresectable, or Metastatic Non-small Cell Lung Cancer or Unresectable or Metastatic Melanoma

50 enrolled

DermatologicThoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Melanoma

NCT00002669 2012-07-02

Combination Chemotherapy, Interferon Alfa, and Interleukin-2 in Treating Patients With Metastatic Melanoma

90 enrolled

Melanoma

NCT00002860 2012-01-13

SWOG-9430: Surgery in Treating Patients With Metastatic Melanoma

77 enrolled