Clinical Trials

Diabetes Mellitus, Insulin-Dependent, 12, Parkinson Disease 4, Autosomal Dominant Lewy Body, Melanoma

NCT00600496 2026-05-27

A Phase I, Open-Label, Multi-center Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD6244 (ARRY-142886)

BreastDermatologicGastrointestinalGenitourinaryThoracic

140 enrolled

Breast Neoplasms, Colonic Neoplasms, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasms

NCT03336606 2026-05-22

Study of MEDI0562 Prior to Surgical Resection in Head and Neck Squamous Cell Carcinoma (HNSCC) or Melanoma

13 enrolled

DermatologicHead & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Melanoma, Neoplasms, Squamous Cell

NCT04253080 2026-05-20

ENZYMELA

127 enrolled

Diabetes Mellitus, Insulin-Dependent, 12, Melanoma

NCT01624220 2026-05-12

A Prospective Study Using Implanted Fiducial Markers to Assess Treatment Accuracy and Esophageal Toxicity in Spinal Stereotactic Body Radiation Therapy

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

41 enrolled 8 charts

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Melanoma, Neoplasms, Unknown Primary, Prostatic Neoplasms, Sarcoma, Spinal Cord Neoplasms, Thyroid Neoplasms

NCT02437227 2026-05-12

PanRAF

31 enrolled 16 charts

Melanoma, Neoplasms

NCT04146064 2026-05-08

Breathomics as Predictive Biomarker for Checkpoint Inhibitor Response

DermatologicGenitourinaryHead & Neck

190 enrolled

Carcinoma, Transitional Cell, Head and Neck Neoplasms, Kidney Neoplasms, Melanoma

NCT03552718 2026-05-07

QUILT-2.025 NANT Neoepitope Yeast Vaccine (YE-NEO-001): Adjuvant Immunotherapy Using a Personalized Neoepitope Yeast-Based Vaccine To Induce T-Cell Responses In Subjects W/ Previously Treated Cancers.

BreastDermatologicGastrointestinalHead & NeckThoracic

5 enrolled

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Liver Neoplasms, Melanoma, Pancreatic Neoplasms, Colorectal Neoplasms

NCT04726319 2026-05-06

FHAMe

BreastDermatologicGastrointestinalGenitourinaryGynecologic

627 enrolled

Breast Neoplasms, Coronary Artery Disease, Diabetes Mellitus, Type 2, Melanoma, Ovarian Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT06463509 2026-05-01

TUPRO

116 enrolled

Melanoma

NCT06151847 2026-04-30

Lifileucel With Reduced Dose Fludarabine/Cyclophosphamide Lymphodepletion and Interleukin-2 for the Treatment of Patients With Unresectable or Metastatic Melanoma

11 enrolled

Melanoma

NCT02576431 2026-04-28

NAVIGATE

BreastDermatologicGastrointestinalHead & NeckSarcomaThoracic

215 enrolled 2 FDA

Biliary Tract Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasms, Salivary Gland Neoplasms, Sarcoma, Thyroid Neoplasms, Colorectal Neoplasms

NCT05421988 2026-04-27

Effectiveness of Group and Individual Training in EFT for Patients in Remission From Melanoma

56 enrolled

870 enrolled 15 charts 1 FDA

Melanoma

NCT01682083 2026-04-21

COMBI-AD

Phase 3 Completed

Melanoma, Neoplasms

NCT03881488 2026-04-17

Study of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced Malignancies

DermatologicHead & NeckOther solid neoplasmThoracic

100 enrolled

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Melanoma, Mesothelioma, Neoplasm Metastasis, Small Cell Lung Carcinoma

NCT03348891 2026-04-14

MELANFα

60 enrolled

Melanoma

NCT05461430 2026-04-13

TraveraRTGx

BreastDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

72 enrolled

Anus Neoplasms, Appendiceal Neoplasms, Ascites, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Laryngeal Neoplasms, Lung Neoplasms, Melanoma, Mesothelioma, Mouth Neoplasms, Nasopharyngeal Neoplasms, Neoplasms, Unknown Primary, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Penile Neoplasms, Stomach Neoplasms, Thymoma, Vulvar Neoplasms, Pleural Effusion, Malignant, Carcinoma, Neuroendocrine, Cholangiocarcinoma, Carcinoma, Small Cell, Carcinoma, Pancreatic Ductal, Gastrointestinal Stromal Tumors

NCT03236935 2026-04-09

Phase Ib of L-NMMA and Pembrolizumab

DermatologicHead & NeckThoracic

12 enrolled 15 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Melanoma, DNA Repair-Deficiency Disorders

NCT02816021 2026-04-06

Study of Oral Azacitidine (CC-486) in Combination With Pembrolizumab (MK-3475) in Patients With Metastatic Melanoma

24 enrolled

Melanoma

NCT05105100 2026-04-06

Peripheral T Cell Determinants of Response and Resistance to Pembrolizumab in Melanoma

25 enrolled 13 charts

Phase EARLY_PHASE1 Completed

Melanoma

NCT05704933 2026-04-06

Pilot Study of Nivolumab w/Ipilimumab or Relatlimab in Surgically Resectable Melanoma Brain Metastases

1 enrolled

CNSDermatologic

Brain Neoplasms, Melanoma

NCT06694571 2026-04-03

STARS

38 enrolled 9 charts

Melanoma, Skin Neoplasms

NCT05628883 2026-04-02

Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma

17 enrolled

Uveal Melanoma, Melanoma

NCT05148325 2026-04-01

Assessment of Safety ,Tolerance and Pharmacokinetics Clinical Efficacy With BAT4706 in Advanced Solid Tumors

28 enrolled

Melanoma

NCT01840007 2026-03-31

Pilot Study Evaluating the Efficacy and Safety of Metformin in Melanoma

20 enrolled

Melanoma

NCT02133222 2026-03-31

AMMAM

22 enrolled

Melanoma, Neoplasm Metastasis

NCT04890028 2026-03-31

DOPACER

BreastCNSDermatologicThoracic

32 enrolled

Brain Neoplasms, Breast Neoplasms, Lung Neoplasms, Melanoma

NCT03293784 2026-03-30

TICIMEL

33 enrolled

Diabetes Mellitus, Insulin-Dependent, 12, Melanoma

NCT03620019 2026-03-27

Denosumab + PD-1 in Subjects With Stage III/ IV Melanoma

25 enrolled 16 charts

Melanoma

NCT05907122 2026-03-27

A Study to Evaluate Similarity of ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Resected Melanoma

Phase 3 Completed

256 enrolled

Melanoma

NCT02360579 2026-03-25

LN-144

220 enrolled 16 charts

Phase EARLY_PHASE1 Completed

Melanoma

NCT03276832 2026-03-19

Imiquimod and Pembrolizumab in Treating Patients With Stage IIIB-IV Melanoma

7 enrolled 11 charts

Melanoma

NCT04960059 2026-03-19

NOTION: iN-home Sampling Of cyTokines in ImmunOtherapy patieNts

DermatologicGenitourinaryThoracic

24 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma, Neoplasms

NCT04423029 2026-03-18

A Study of DF6002 Alone and in Combination With Nivolumab

170 enrolled

DermatologicThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma

NCT06108479 2026-03-18

Study of DF6215 in Patients With Advanced Solid Tumors

DermatologicGenitourinaryGynecologicHead & NeckThoracic

35 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Head and Neck Neoplasms, Melanoma, Neoplasms, Ovarian Neoplasms

NCT03070392 2026-03-17

Safety and Efficacy of IMCgp100 Versus Investigator Choice in Advanced Uveal Melanoma

378 enrolled 15 charts 1 FDA

Uveal Melanoma, Melanoma

NCT04609566 2026-03-16

Brentuximab Vedotin With Pembrolizumab in Metastatic Solid Tumors

DermatologicHead & NeckThoracic

161 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Melanoma

NCT06221397 2026-03-16

LEGIT_MC_EVCDA

105 enrolled 15 charts

Disease, Melanoma

NCT06894771 2026-03-16

MK-4700-001

BreastDermatologicGenitourinaryGynecologicHead & NeckThoracic

5 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Melanoma, Neoplasms, Triple Negative Breast Neoplasms

NCT02410733 2026-03-12

Lipo-MERIT

119 enrolled

Melanoma

NCT03239145 2026-03-12

Pembrolizumab (Anti-PD-1) and AMG386 (Angiopoietin-2 (Ang-2) in Patients With Advanced Solid Tumor

DermatologicGastrointestinalGenitourinaryGynecologic

62 enrolled 17 charts

Kidney Neoplasms, Melanoma, Ovarian Neoplasms, Colorectal Neoplasms

NCT02858869 2026-03-09

Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain Metastases

25 enrolled 14 charts

CNSDermatologicThoracic

Uveal Melanoma, Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma

NCT01336270 2026-03-06

IMMUMELA

217 enrolled