Announcements Trials
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Phase

Phase 1/2 2Phase 1 1

Status

Completed 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2

Conditions

Multiple Myeloma 132Recurrence 33Precursor Cell Lymphoblastic Leukemia-Lymphoma 23Neoplasms, Plasma Cell 15Neoplasms 10Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 8Leukemia 7Immunoglobulin Light-chain Amyloidosis 7Lymphoma, Non-Hodgkin 6Amyloidosis 6Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 5Lymphoma, Large B-Cell, Diffuse 5Lymphoma 5Hematologic Neoplasms 5Carcinoma, Non-Small-Cell Lung 5Burkitt Lymphoma 5Paraproteinemias 4Lymphoma, Mantle-Cell 4Leukemia, Myeloid, Acute 4Hematologic Diseases 4Blood Protein Disorders 4Neoplasm Metastasis 3Myelodysplastic Syndromes 3Lymphoma, B-Cell 3Lung Neoplasms 3Esophageal Neoplasms 3Corneal Diseases 3Triple Negative Breast Neoplasms 2Small Cell Lung Carcinoma 2Prostatic Neoplasms 2

Interventions

Pemetrexed 7Radiotherapy 3Trastuzumab 2Dexamethasone 2toripalimab 1sacituzumab govitecan 1pertuzumab 1Vitamin B 12 1Rituximab 1Folic Acid 1Bevacizumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1/2 × Meningeal Carcinomatosis × Dexamethasone × Clear all
NCT05289908 2025-05-04

Intrathecal Pemetrexed for Leptomeningeal Metastasis

The First Hospital of Jilin University

Phase 1/2 Completed
34 enrolled
CNS

Meningeal Carcinomatosis

NCT03507244 2019-12-26

Concurrent Intrathecal-pemetrexed and Involved-field Radiotherapy for Leptomeningeal Metastasis From Solid Tumors

The First Hospital of Jilin University

Phase 1/2 Completed
34 enrolled
CNS

Meningeal Carcinomatosis

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