Announcements Trials
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Phase

Phase 1/2 1Phase 1 1

Status

Completed 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2

Conditions

Polycystic Ovary Syndrome 17Colorectal Neoplasms 7Lung Neoplasms 4Ovarian Neoplasms 3Infertility 3Breast Neoplasms 3Uterine Cervical Neoplasms 2Recurrence 2Neoplasms 2Meningeal Carcinomatosis 2Insulin Resistance 2Infertility, Female 2Hyperandrogenism 2Diabetes, Gestational 2Carcinoma, Non-Small-Cell Lung 2Atypical Squamous Cells of the Cervix 2Anemia 2Uterine Cervical Dysplasia 1Urinary Bladder Neoplasms 1Ureteral Neoplasms 1Thrombocytopenia 1Stroke 1Stomatitis 1Stomach Neoplasms 1Squamous Intraepithelial Lesions 1Rectal Neoplasms 1Psoriasis 1Prostatic Neoplasms 1Preventive Effect of Quintuple Therapy on Metachronous Liver Metastases in Patients With Colorectal Cancer 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1

Interventions

Pemetrexed 18Bevacizumab 9Spinal Puncture 7Radiotherapy 7Specimen Handling 5Methotrexate 5Magnetic Resonance Spectroscopy 5osimertinib 4aflutinib 4Trastuzumab 3Topotecan 3Temozolomide 3Dexamethasone 3trastuzumab deruxtecan 2pembrolizumab 2merphos 2lorlatinib 2Vitamin B 12 2Rituximab 2Radiotherapy, Intensity-Modulated 2Folic Acid 2Drug Therapy 2Cytarabine 2Cyclophosphamide 2tucatinib 1toripalimab 1sintilimab 1sacituzumab govitecan 1pertuzumab 1peginterferon alfa-2b 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
OTHER × Meningeal Carcinomatosis × Folic Acid × Clear all
NCT05289908 2025-05-04

Intrathecal Pemetrexed for Leptomeningeal Metastasis

The First Hospital of Jilin University

Phase 1/2 Completed
34 enrolled
CNS

Meningeal Carcinomatosis

NCT03101579 2019-03-19

Intrathecal Pemetrexed for Recurrent Leptomeningeal Metastases From Non-small Cell Lung Cancer

The First Hospital of Jilin University

Phase 1 Completed
13 enrolled
CNS

Recurrence, Meningeal Carcinomatosis

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