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Phase

Phase 1 1

Status

Active not recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1Breast 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 20Lymphoma, B-Cell 17Lymphoma, Large B-Cell, Diffuse 16Lymphoma, Non-Hodgkin 13Multiple Myeloma 11Recurrence 10Burkitt Lymphoma 10Lymphoma, Mantle-Cell 8Lymphoma 8Leukemia, Myeloid, Acute 8Carcinoma, Hepatocellular 7Pancreatic Neoplasms 6Lymphoma, Follicular 6Leukemia, Lymphocytic, Chronic, B-Cell 6Neoplasms 5Leukemia 5Glioma 5Colorectal Neoplasms 5Stomach Neoplasms 4Leukemia, B-Cell 4Neoplasm, Residual 3Nasopharyngeal Carcinoma 3Melanoma 3Esophageal Neoplasms 3Breast Neoplasms 3Simpson-Golabi-Behmel syndrome 2Sarcoma, Synovial 2Sarcoma, Ewing 2Rhabdomyosarcoma 2Ovarian Neoplasms 2

Interventions

Pemetrexed 19Bevacizumab 10Radiotherapy 8Spinal Puncture 7osimertinib 6Methotrexate 6Magnetic Resonance Spectroscopy 6aflutinib 5Topotecan 5Specimen Handling 5Trastuzumab 4Temozolomide 4Radiotherapy, Intensity-Modulated 4Dexamethasone 3trastuzumab deruxtecan 2pembrolizumab 2omburtamab I-131 2merphos 2aumolertinib 2WP 744 2Vitamin B 12 2Rituximab 2Radiation 2Folic Acid 2Drug Therapy 2Cytarabine 2Cyclophosphamide 2Capecitabine 2Busulfan 2AZD3759 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Interventional × Meningeal Carcinomatosis × Immunotherapy, Adoptive × Clear all
NCT03696030 2026-04-23

HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases

City of Hope Medical Center

Phase 1 Active not recruiting
24 enrolled
BreastCNS

Brain Neoplasms, Breast Neoplasms, Neoplasms, Meningeal Carcinomatosis

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