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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Other hematologic neoplasm 1Lymphoid 1Gynecologic 1CNS 1

Conditions

Multiple Myeloma 192Lymphoma 102Lymphoma, Non-Hodgkin 90Leukemia, Myeloid, Acute 89Precursor Cell Lymphoblastic Leukemia-Lymphoma 81Myelodysplastic Syndromes 81Hodgkin Disease 67Leukemia 66Neoplasms, Plasma Cell 65Lymphoma, Large B-Cell, Diffuse 59Leukemia, Lymphocytic, Chronic, B-Cell 58Lymphoma, Mantle-Cell 52Lymphoma, Follicular 49Burkitt Lymphoma 39Lymphoma, Large-Cell, Immunoblastic 35Lymphoma, B-Cell, Marginal Zone 34Myeloproliferative Disorders 30Recurrence 28Hematologic Neoplasms 28Neuroblastoma 25Leukemia, Myelogenous, Chronic, BCR-ABL Positive 25Leukemia, Myeloid, Accelerated Phase 24Graft vs Host Disease 23Leukemia, Myelomonocytic, Chronic 22Leukemia, Myeloid, Chronic-Phase 22Congenital Abnormalities 21Immunoglobulin Light-chain Amyloidosis 20Dendritic Cell Sarcoma, Interdigitating 19Primary Myelofibrosis 18Waldenstrom Macroglobulinemia 17

Interventions

Pemetrexed 18Bevacizumab 9Spinal Puncture 7Radiotherapy 7Specimen Handling 5Methotrexate 5Magnetic Resonance Spectroscopy 5osimertinib 4aflutinib 4Trastuzumab 3Topotecan 3Temozolomide 3Dexamethasone 3trastuzumab deruxtecan 2pembrolizumab 2merphos 2lorlatinib 2Vitamin B 12 2Rituximab 2Radiotherapy, Intensity-Modulated 2Folic Acid 2Drug Therapy 2Cytarabine 2Cyclophosphamide 2tucatinib 1toripalimab 1sintilimab 1sacituzumab govitecan 1pertuzumab 1peginterferon alfa-2b 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
OTHER × Meningeal Carcinomatosis × Melphalan × Clear all
NCT00002750 2013-02-20

Melphalan in Patients With Neoplastic Meningitis

Duke University

Phase 1 Completed
6 enrolled
CNSGynecologicLymphoidOther hematologic neoplasmSarcoma

Burkitt Lymphoma, Hodgkin Disease, Leukemia, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Ovarian Neoplasms, Recurrence, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Acute, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Central Nervous System Neoplasms, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating, Meningeal Carcinomatosis

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